Butane

Butane

SCHEMBL321302

CCCC.CCOC(OC(=O)CC(=O)O)OC(=O)CC(=O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
FFAR3 O14843 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
LDHA P00338 1/20 0.31
SRR Q9GZT4 1/20 0.31
FAAH O00519 4/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1543387 0.96 THRB (0.42) THRBMGAMGAASIMGAM2
SCHEMBL10532061 0.80 FFAR1 (0.42) HDAC3HDAC1HDAC2HDAC8CNR2
Butane SCHEMBL10826497 0.80 ALOX15 (0.36) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL10779438 0.78 LMNA (0.44) MGAMGAASIMGAM2FFAR3
Butane SCHEMBL10375749 0.77
Butane SCHEMBL452862 0.77 LMNA (0.50) GAAFFAR3HDAC3HDAC1HDAC2
Butane SCHEMBL3687712 0.77 LDHA (0.35) MGAMGAASIMGAM2FFAR3
Butane SCHEMBL3319065 0.75 FFAR3 (0.33) MGAMGAASIMGAM2FFAR3
Butane SCHEMBL9588839 0.74 FAAH (0.30) FAAHCNR1CNR2
SCHEMBL6270772 0.74 TSHR (0.38) MGAMGAASIMGAM2LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111747890-B Preparation method of 4, 7-dichloroquinoline 重庆医药高等专科学校 2025-05-09 CN claimed
CN-115774065-B GC detection method for diethyl ethoxymethylene malonate 武汉海特生物创新医药研究有限公司 2025-04-01 CN claimed
CN-119306697-A 4-Quinolinone derivative and preparation method and application thereof 山东大学 2025-01-14 CN claimed
CN-118160746-B Bactericide for preventing and treating diseases of leaves and fruits and preparation method thereof 潍坊奥丰作物病害防治有限公司 2024-08-02 CN claimed
CN-118160746-A Bactericide for preventing and treating diseases of leaves and fruits and preparation method thereof 潍坊奥丰作物病害防治有限公司 2024-06-11 CN claimed
CN-116200183-B High-efficiency variable-viscosity fracturing fluid for deep coal bed gas development and integrated construction method 四川申和新材料科技有限公司 2024-05-28 CN claimed
CN-115109595-B Saline-alkali soil composite soil conditioner and preparation method and application thereof 北京晋荣农业科技有限公司 2024-05-07 CN claimed
CN-117624046-A Synthesis method of ethoxylomefloxacin 江苏吉贝尔药业股份有限公司 2024-03-01 CN claimed
CN-113880757-B Method for synthesizing 4-pyridone and derivatives thereof through continuous flow 云南民族大学 2024-02-06 CN claimed
CN-115057847-B Preparation method of 4, 6-dichloro-5- (1, 3-dioxolan-2-yl) -2-methylpyrimidine 山东百启生物医药有限公司 2024-01-26 CN claimed
CN-113880757-A Method for synthesizing 4-pyridone and derivatives thereof by continuous flow 云南民族大学 2022-01-04 CN claimed
CN-112939942-A Heterocyclic ester compound containing quinoline structure and preparation method and application thereof 聊城大学 2021-06-11 CN claimed
CN-112480008-A Synthesis method of 1-methyl-5-hydroxypyrazole 浙江工业大学 2021-03-12 CN claimed
CN-112062720-A Continuous preparation method of 1-methyl-3-hydroxypyrazole-4-carboxylic acid ethyl ester 江苏七洲绿色化工股份有限公司 2020-12-11 CN claimed
CN-111747890-A Preparation method of 4, 7-dichloroquinoline 重庆医药高等专科学校 2020-10-09 CN claimed
CN-111559982-A 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof 天津市医药科学研究所 2020-08-21 CN claimed
CN-107629001-B Synthesis method of anticancer drug lenvatinib 重庆大学 2020-07-21 CN claimed
CN-111393298-A Green pepper flavor compound, preparation method thereof, food additive and green pepper flavor food 东莞波顿香料有限公司 2020-07-10 CN claimed
WO-1999006400-A1 PYRAZOLOQUINOLINONE DERIVATIVES AS GABA ALPHA 5 RECEPTOR INVERSE AGONISTS MERCK SHARP & DOHME LIMITED (GB) 1999-02-11 WO claimed
WO-1999006399-A1 ARYL-SUBSTITUTED PYRAZOLOQUINOLINONE DERIVATIVES AS GABA ALPHA 5 RECEPTOR INVERSE AGONISTS MERCK SHARP & DOHME LIMITED (GB) 1999-02-11 WO claimed