Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226659 | 0.80 | CYP19A1 (0.47) | KCNA5CYP19A1CHRNB2CHRNA4KDM4E | |
| SCHEMBL812047 | 0.77 | ALDH1A1 (0.44) | NR1H2NR1H3KDM4E | |
| SCHEMBL26479501 | 0.76 | CYP19A1 (0.49) | KCNA5CYP19A1LMNACYP1A2CYP3A4 | |
| SCHEMBL13684207 | 0.73 | CYP19A1 (0.46) | KCNA5CYP19A1KDM4ELMNACYP1A2 | |
| SCHEMBL13557773 | 0.72 | CYP19A1 (0.55) | KCNA5CYP19A1LMNACYP1A2CYP3A4 | |
| SCHEMBL28036808 | 0.72 | CYP19A1 (0.55) | KCNA5CYP19A1LMNACYP1A2CYP3A4 | |
| SCHEMBL29387897 | 0.72 | CYP19A1 (0.57) | KCNA5CYP19A1CYP1A2CYP3A4KIF11 | |
| SCHEMBL7068828 | 0.72 | CYP19A1 (0.57) | KCNA5CYP19A1CYP1A2CYP3A4KIF11 | |
| SCHEMBL13577 | 0.72 | CYP19A1 (0.57) | KCNA5CYP19A1CYP1A2CYP3A4KIF11 | |
| SCHEMBL3431565 | 0.71 | CYP19A1 (0.45) | KCNA5CYP19A1LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439170-B1 | Fluorinating reactants and process for their preparation | SALTIGO GMBH (DE) | 2009-06-03 | — | — | EP | claimed |
| US-7045662-B2 | α, α-difluoroamines and difluoromethylene-α, α-diazo compounds | BAYER CHEMICALS AG (DE) | 2006-05-16 | — | — | US | claimed |
| US-20050085474-A1 | Fluorinating reagents and their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-21 | — | — | US | claimed |
| US-20040198975-A1 | Alpha, alpha-difluoroamines and difluoromethylene-alpha, alpha-diazo compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | claimed |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | disclosed |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | disclosed |
| US-7045662-B2 | α, α-difluoroamines and difluoromethylene-α, α-diazo compounds | BAYER CHEMICALS AG (DE) | 2006-05-16 | — | — | US | disclosed |
| US-20050085474-A1 | Fluorinating reagents and their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-21 | — | — | US | disclosed |
| US-20040198975-A1 | Alpha, alpha-difluoroamines and difluoromethylene-alpha, alpha-diazo compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | disclosed |
| EP-1437342-A2 | Fluorinating reactants and process for their preparation | Bayer Chemicals AG (DE) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198975-A1 | Alpha, alpha-difluoroamines and difluoromethylene-alpha, alpha-diazo compounds | DDT, DDO, SAT1 | KCNA5 2088/4885CYP19A1 362/4885CHRNB2 822/4885 |
| US-20050085474-A1 | Fluorinating reagents and their preparation | FLNA, ARFGEF1, FLNB | KCNA5 2236/4885CYP19A1 1245/4885CHRNB2 1628/4885 |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | FLNA, ARFGEF1, FLNB | KCNA5 2236/4885CYP19A1 1245/4885CHRNB2 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.