Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812265 | 0.88 | KIF11 (0.52) | ALDH1A1CYP2C9TAAR1NR1H2NR1H3 | |
| SCHEMBL812665 | 0.80 | TSHR (0.41) | TSHRRORCCA1CA2CA5A | |
| SCHEMBL5891888 | 0.79 | BCL2 (0.37) | ALDH1A1MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL3213108 | 0.78 | MEN1 (0.40) | TSHRMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL295494 | 0.78 | LMNA (0.40) | MEN1KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1337600 | 0.77 | PTPN1 (0.46) | SIGMAR1CYP2D6PTPN1 | |
| SCHEMBL3213096 | 0.77 | KCNA5 (0.46) | NR1H2NR1H3KDM4E | |
| SCHEMBL10745740 | 0.76 | KCNN4 (0.54) | ALDH1A1TSHRKCNN4SIGMAR1MEN1 | |
| SCHEMBL3049242 | 0.76 | KCNN4 (0.43) | ALDH1A1TSHRKCNN4SIGMAR1MEN1 | |
| SCHEMBL1338196 | 0.75 | CA12 (0.42) | ALDH1A1MEN1KMT2AMAPK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251674-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BioCryst Pharmaceuticals, Inc. (US) | 2017-12-06 | — | — | EP | disclosed |
| US-20170267681-A1 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | MIDCAP FINANCIAL TRUST, AS AGENT | 2017-09-21 | — | — | US | disclosed |
| EP-2243769-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE FLUOROAMINE | CENTRAL GLASS CO LTD (JP) | 2017-06-28 | — | — | EP | disclosed |
| US-20150291596-A1 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BIOCRYST PHARMACEUTICALS, INC. | 2015-10-15 | — | — | US | disclosed |
| US-8203003-B2 | 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods | UBE INDUSTRIES, LTD. (JP) | 2012-06-19 | — | — | US | disclosed |
| US-8063205-B2 | Method for producing 2-oxazoline analogue or 1,3-oxazine analogue | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2011-11-22 | — | — | US | disclosed |
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | UBE INDUSTRIES, LTD. (JP) | 2011-11-10 | — | — | US | disclosed |
| US-7968751-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7892518-B2 | fluorinating a specific position of a saccharide substrate selectively without affecting a protective group at a temperature within a wide range safely and easily with N, N-diethyl-alpha, alpha-difluoro(3-methyl)benzylamine a fluorinating agent under irradiation with microwave or electromagnetic wave | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-02-22 | — | — | US | disclosed |
| WO-2010081014-A1 | NOVEL 4-FLUOROPYRROLIDINE-2-CARBONYL FLUORIDE COMPOUNDS AND THEIR PREPARATIVE METHODS | IM&T RESEARCH, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | disclosed |
| US-20090281309-A1 | METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20080319228-A1 | Method of fluorination | HARA SHOJI | 2008-12-25 | — | — | US | disclosed |
| EP-1956012-A1 | METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE | National University Corporation Hokkaido University (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20080154064-A1 | Method of fluorination | HARA SHOJI | 2008-06-26 | — | — | US | disclosed |
| US-7351863-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20060014972-A1 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-01-19 | — | — | US | disclosed |
| EP-1568703-A1 | METHOD OF FLUORINATION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-20050085474-A1 | Fluorinating reagents and their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-21 | — | — | US | disclosed |
| EP-1437342-A2 | Fluorinating reactants and process for their preparation | Bayer Chemicals AG (DE) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | PFAS, AFF4, PAICS | ALDH1A1 916/4885TSHR 2379/4885KCNN4 165/4885 |
| US-20080154064-A1 | Method of fluorination | FUCA2, FABP2, FGB | ALDH1A1 1770/4885TSHR 2253/4885KCNN4 1487/4885 |
| US-20150291596-A1 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | RNGTT, DUT, RNMT | ALDH1A1 2817/4885TSHR 4358/4885KCNN4 3720/4885 |
| US-20050085474-A1 | Fluorinating reagents and their preparation | FLNA, ARFGEF1, FLNB | ALDH1A1 362/4885TSHR 1608/4885KCNN4 4717/4885 |
| US-20080319228-A1 | Method of fluorination | FUCA2, FABP2, FGB | ALDH1A1 1770/4885TSHR 2253/4885KCNN4 1487/4885 |
| US-20090281309-A1 | METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE | OXA1L, SULT1A1, DAO | ALDH1A1 41/4885TSHR 1049/4885KCNN4 3579/4885 |
| US-20170267681-A1 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | RNGTT, DUT, RNMT | ALDH1A1 2817/4885TSHR 4358/4885KCNN4 3720/4885 |
| US-20060014972-A1 | Method of fluorination | FUCA2, FABP2, FGB | ALDH1A1 1770/4885TSHR 2253/4885KCNN4 1487/4885 |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | FLNA, ARFGEF1, FLNB | ALDH1A1 362/4885TSHR 1608/4885KCNN4 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.