Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193635 | 0.88 | HDAC8 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29278340 | 0.86 | EPHX2 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Biphenyl SCHEMBL28145666 | 0.85 | MTNR1A (0.40) | HDAC1CTSK | |
| SCHEMBL28302938 | 0.85 | HDAC3 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL31301833 | 0.85 | ANPEP (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4230480 | 0.85 | EPHX2 (0.40) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL19143345 | 0.84 | HDAC3 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL22151802 | 0.84 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1555914 | 0.83 | GABRP (0.50) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL5197380 | 0.83 | GABRP (0.50) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116500858-A | Coating of combined photoresist and Si-based hard mask | 上海艾深斯科技有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-119019417-A | Pyrazole five-membered ring macrocyclic derivative and preparation method and application thereof | 山东绿叶制药有限公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-3375774-B1 | PHENALEN-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALEN-1-ONE COMPOUNDS AND THEIR USE | JUFICO GMBH (DE) | 2024-11-13 | — | — | EP | disclosed |
| US-11987557-B2 | Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof | TRIOPTOTEC GMBH (DE) | 2024-05-21 | — | — | US | disclosed |
| CN-115380026-B | Protein degradation modulators and methods of use thereof | 南京明德新药研发有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116500858-A | Coating of combined photoresist and Si-based hard mask | 上海艾深斯科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-114560850-A | Near-infrared fluorescent molecular probe, and preparation method and application thereof | 中国药科大学 | 2022-05-31 | — | — | CN | disclosed |
| US-20220064114-A1 | PHENALENE-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALENE-1-ONE COMPOUND AND THE USE THEREOF | TRIOPTOTEC GMBH (DE) | 2022-03-03 | — | — | US | disclosed |
| US-11186545-B2 | Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof | TRIOPTOTEC GMBH (DE) | 2021-11-30 | — | — | US | disclosed |
| CN-111253370-B | N-polysubstituted pyridine-2-aminopyrimidine derivatives and application thereof | 浙江大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-1077109-C | S type 2-substituted hydroxy-2-indolidinylbutyric ester compound and preparation method thereof | TANABE SEIYAKU CO (JP) | 2002-01-02 | — | — | CN | disclosed |
| US-6299597-B1 | Percutaneous repair of cardiovascular anomalies and repair compositions | SCIMED LIFE SYSTEMS, INC. | 2001-10-09 | — | — | US | disclosed |
| CN-1313286-A | S-type 4-substituted hydroxypyranoindolidine compound and its derivative and preparation method thereof | TANABE SEIYAKU CO (JP) | 2001-09-19 | — | — | CN | disclosed |
| WO-2001004134-A2 | NOVEL ESTERS DERIVED FROM NUCLEOSIDES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRES LAPHAL S.A. (FR) | 2001-01-18 | — | — | WO | disclosed |
| EP-0999856-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | Du Pont Pharmaceuticals Company (US) | 2000-05-17 | — | — | EP | disclosed |
| CN-1239895-A | Radiopharmaceuticals for imaging sites of infection and inflammation | DU PONT MERCK PHARMA (US) | 1999-12-29 | — | — | CN | disclosed |
| CN-1183414-A | S-type 2-substituted hydroxy-2-indolidinylbutyric ester compound and process for producing the same | TANABE SEIYAKU CO (JP) | 1998-06-03 | — | — | CN | disclosed |
| WO-1998015295-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | DUPONT PHARMACEUTICALS COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| US-5468854-A | Characterization of specific drug receptors with fluorescent ligands | PHARMACEUTICAL DISCOVERY CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| WO-1995008289-A2 | PERCUTANEOUS REPAIR OF CARDIOVASCULAR ANOMALIES AND REPAIR COMPOSITIONS | SCIMED LIFE SYSTEMS, INC. (US) | 1995-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11987557-B2 | Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof | PYCR1, CRY1, PPOX | HDAC3 3465/4885HDAC1 1229/4885HDAC2 2897/4885 |
| US-11186545-B2 | Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof | PYCR1, CRY1, PPOX | HDAC3 3465/4885HDAC1 1229/4885HDAC2 2897/4885 |
| US-20220064114-A1 | PHENALENE-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALENE-1-ONE COMPOUND AND THE USE THEREOF | PYCR1, CRY1, PPOX | HDAC3 3465/4885HDAC1 1229/4885HDAC2 2897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.