SCHEMBL321437

SCHEMBL321437

CC1(C)OB(c2ccncc2)OC1(C)C

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LPL P06858 13/20 0.53
LIPG Q9Y5X9 13/20 0.53
F11 P03951 1/20 0.47
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
CA12 O43570 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
ESR2 Q92731 1/20 0.40
P4HB P07237 1/20 0.38
FFAR1 O14842 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28602416 0.89 LIPG (0.49) LPLLIPGF11CA1CA2
SCHEMBL1372253 0.88 LIPG (0.67) LPLLIPGF11CA1CA2
SCHEMBL30381735 0.86 LPL (0.46) LPLLIPGF11CA1CA2
SCHEMBL3517704 0.83 LIPG (0.67) LPLLIPGF11CA1CA2
SCHEMBL19489213 0.83 LPL (0.45) LPLLIPGF11CA1CA2
SCHEMBL18123774 0.83 CA1 (0.51) LPLLIPGF11CA1CA2
SCHEMBL228212 0.83 LPL (0.71) LPLLIPGF11CA1CA2
SCHEMBL15803153 0.81 LIPG (0.49) LPLLIPGF11CA1CA2
SCHEMBL25981590 0.80 LPL (0.47) LPLLIPGF11CA1CA2
SCHEMBL27905476 0.79 LPL (0.36) LPLLIPGF11CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375089-A Photosensitizer with high singlet oxygen yield and preparation method thereof 山东大学 2021-02-19 CN claimed
CN-106532120-A Non-aqueous electrolyte and lithium secondary battery of using same 广州天赐高新材料股份有限公司 2017-03-22 CN claimed
EP-4743455-A1 SARM1 INHIBITORS F. Hoffmann-La Roche AG (CH) 2026-05-20 EP disclosed
EP-4105216-B1 DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF GENFLEET THERAPEUTICS SHANGHAI INC (CN) 2026-05-20 EP disclosed
US-20260132122-A1 6-6-FUSED BICYCLIC HETEROARYL AMINES AS CDK4 INHIBITORS INCYTE CORP (US) 2026-05-14 US disclosed
US-12617797-B2 Substituted pyrazolo [1,5-a]pyrimidines having multimodal activity against pain ESTEVE PHARMACEUTICALS, S.A. (ES) 2026-05-05 US disclosed
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof MBD Co., Ltd. (KR) 2026-04-28 US disclosed
US-12606558-B2 Condensed pyrazole derivatives as inhibitors of SARM1 DISARM THERAPEUTICS, INC. (US) 2026-04-21 US disclosed
EP-4713095-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS Chengdu Anticancer Bioscience, Ltd. (CN) 2026-03-25 EP disclosed
US-20260071117-A1 FUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF UNIV ARIZONA (US) 2026-03-12 US disclosed
US-12565492-B2 Anaplastic Lymphoma Kinase (ALK) degraders and uses thereof TRIANA BIOMEDICINES, INC. (US) 2026-03-03 US disclosed
US-20040122001-A1 Pharmaceutical compounds ELI LILLY AND COMPANY 2004-06-24 US disclosed
US-20040023963-A1 Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases CAO JINGRONG (US) 2004-02-05 US disclosed
US-6642227-B2 Such as 2-methylsulfanyl-5-(2-phenylamino-pyrimidin-4-yl)-4-p-tolyl-thiophene-3 -carbonitrile; antiproliferative agents; stents VERTEX PHARMACEUTICALS INCORPORATED 2003-11-04 US disclosed
EP-1345930-A2 PHARMACEUTICAL COMPOUNDS ELI LILLY AND COMPANY (US) 2003-09-24 EP disclosed
US-20030096816-A1 Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases VERTEX PHARMACEUTICALS INCORPORATED 2003-05-22 US disclosed
WO-2002096913-A1 SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES GENTIAN AS (NO) 2002-12-05 WO disclosed
EP-1238016-A1 SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS Gentian AS (NO) 2002-09-11 EP disclosed
WO-2002050067-A2 PHARMACEUTICAL HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 2002-06-27 WO disclosed
WO-2001042368-A1 SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS GENTIAN AS (NO) 2001-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023963-A1 Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases LCK, MAPK1, MAP3K1 LPL 3701/4885LIPG 2802/4885F11 2331/4885
US-12617797-B2 Substituted pyrazolo [1,5-a]pyrimidines having multimodal activity against pain SIGMAR1, OPRD1, OPRL1 LPL 3434/4885LIPG 4125/4885F11 1642/4885
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof CYP4A11, CYP4B1, CYP4A22 LPL 856/4885LIPG 1084/4885F11 4397/4885
US-12606558-B2 Condensed pyrazole derivatives as inhibitors of SARM1 SARM1, SMN1; SMN2, PMP22 LPL 3342/4885LIPG 2573/4885F11 2574/4885
US-20260132122-A1 6-6-FUSED BICYCLIC HETEROARYL AMINES AS CDK4 INHIBITORS CCNA1, CDK4, CCNO LPL 3977/4885LIPG 4600/4885F11 3453/4885
US-20260071117-A1 FUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF H1-3, NISCH, H1-2 LPL 4720/4885LIPG 4824/4885F11 2944/4885
US-20030096816-A1 Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases LCK, MAPK1, MAP3K1 LPL 3701/4885LIPG 2802/4885F11 2331/4885
US-12565492-B2 Anaplastic Lymphoma Kinase (ALK) degraders and uses thereof ALK, NTRK3, NTRK1 LPL 742/4885LIPG 1981/4885F11 3058/4885
US-20040122001-A1 Pharmaceutical compounds CYP2D6, LPXN, CYP1B1 LPL 3899/4885LIPG 4118/4885F11 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.