Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.59 |
| ▸ | MAOB | P27338 | 9/20 | 0.59 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 4/20 | 0.47 |
| ▸ | GABRD | O14764 | 4/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.47 |
| ▸ | GABRE | P78334 | 4/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065762 | 0.84 | FTO (0.61) | MAOAMAOBFTOACHEKDM4E | |
| SCHEMBL30771801 | 0.84 | FTO (0.61) | MAOAMAOBFTOACHEKDM4E | |
| SCHEMBL365385 | 0.78 | MAOA (0.58) | MAOAMAOBFTOACHEDYRK1A | |
| SCHEMBL3681299 | 0.76 | FTO (0.61) | MAOAMAOBFTOACHEDYRK1A | |
| SCHEMBL7617877 | 0.76 | FTO (0.72) | MAOAMAOBFTOACHEDYRK1A | |
| SCHEMBL1094182 | 0.76 | MAOA (0.59) | MAOAMAOBFTOACHEDYRK1A | |
| SCHEMBL21303291 | 0.76 | MAOA (0.53) | MAOAMAOBFTOACHEDYRK1A | |
| SCHEMBL932337 | 0.76 | MAOA (0.59) | MAOAMAOBFTOACHEDYRK1A | |
| SCHEMBL13665731 | 0.76 | MAOA (0.53) | MAOAMAOBFTOACHEDYRK1A | |
| SCHEMBL1166873 | 0.76 | DYRK1A (0.58) | MAOAMAOBFTOACHEDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285925-A | Ratio fluorescence and colorimetric dual-mode reagent for detecting ethylenediamine based on electron energy transfer mechanism | 中国科学院新疆理化技术研究所 | 2023-12-26 | — | — | CN | claimed |
| CN-109053731-B | P-chloro-substituted pyridazinone-structure-containing spiro [ indolizine-pyrazoline ] derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2020-07-07 | — | — | CN | claimed |
| CN-109232570-B | Pyridazinone structure-containing spiro [ indolizine-pyrazoline ] derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2020-07-07 | — | — | CN | claimed |
| CN-109180676-B | 3,4, 5-trimethoxy substituted pyridazinone structure-containing spiro [ indolizine-pyrazoline ] derivative and preparation method thereof | 绍兴文理学院元培学院 | 2020-07-07 | — | — | CN | claimed |
| CN-109232572-B | P-methyl-substituted pyridazinone-structure-containing spiro [ indolizine-pyrazoline ] derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2020-06-23 | — | — | CN | claimed |
| CN-109232571-B | P-methylmercapto-substituted pyridazinone structure-containing spiro [ indolizine-pyrazoline ] derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2020-06-23 | — | — | CN | claimed |
| CN-109053732-B | Para-fluorine substituted pyridazinone structure-containing spiro [ indolizine-pyrazoline ] derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2020-06-23 | — | — | CN | claimed |
| CN-109180675-B | P-methoxy substituted pyridazinone structure-containing spiro [ indolizine-pyrazoline ] derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2020-06-23 | — | — | CN | claimed |
| CN-107674082-B | A kind of preparation method and applications of the D-phenylalanine ring substituent norcantharidin derivative of the structure containing pyridazinone | 绍兴文理学院 | 2019-07-16 | — | — | CN | claimed |
| CN-107674083-B | A kind of preparation method and applications of the L-Leu ring substituent norcantharidin derivative of the structure containing pyridazinone | 绍兴文理学院 | 2019-07-16 | — | — | CN | claimed |
| CN-106046019-A | L-valine-substituted norcantharidin derivative and preparation method and application thereof | 绍兴文理学院 | 2016-10-26 | — | — | CN | claimed |
| CN-105924445-A | Pyrazole-type N-p-nitrophenyl maleimide derivative containing chromone structure, and preparation method and application thereof | 绍兴文理学院 | 2016-09-07 | — | — | CN | claimed |
| CN-105906633-A | Pyrazole-type N-phenyl maleimide derivative with chromone structure, and preparation method and application thereof | 绍兴文理学院 | 2016-08-31 | — | — | CN | claimed |
| CN-105906632-A | Pyrazole-type N-p-methylphenyl maleimide derivative with chromone structure, and preparation method and application thereof | 绍兴文理学院 | 2016-08-31 | — | — | CN | claimed |
| CN-105906634-A | 3-(6-bromine-4-oxygen-4H-chromone)-1-phenyl-5-p-methoxyphenyl-1, 6a-pyrroline (3, 4-c) pyrazole-4, 6(3aH, 5H)-diketone and preparation method and application thereof | 绍兴文理学院 | 2016-08-31 | — | — | CN | claimed |
| CN-105859724-A | 3-(6-bromo-4-oxy-4H-chromone)-1-phenyl-5-p-chlorphenyl-1,6a-dihydro pyrroline[3,4-c] pyrazole-4,6(3aH,5H)-diketone and preparation method and application thereof | 绍兴文理学院 | 2016-08-17 | — | — | CN | claimed |
| CN-103554122-B | A kind of containing chromone structure pyrazoles norcantharidin derivative and preparation method thereof and application | SHAOXING UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-103554135-B | A kind of containing chromone structure isoxazole norcantharidin derivative and preparation method thereof and application | SHAOXING UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-103554122-A | Chromone structure-containing pyrazole norcantharidin derivative as well as preparation method and application thereof | UNIV SHAOXING | 2014-02-05 | — | — | CN | claimed |
| CN-103554135-A | Chromone structure containing isoxazole norcantharidin derivatives as well as preparation method and application thereof | UNIV SHAOXING | 2014-02-05 | — | — | CN | claimed |