Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.59 |
| ▸ | MAOB | P27338 | 6/20 | 0.59 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903208 | 0.84 | FTO (0.61) | MAOAMAOBFTOMAPTHTT | |
| SCHEMBL31297753 | 0.83 | MAOA (0.45) | MAOAMAOBFTOMAPTHTT | |
| Ethane SCHEMBL27840767 | 0.78 | MAOA (0.55) | MAOAMAOBFTOKDM4EALDH1A1 | |
| SCHEMBL365385 | 0.78 | MAOA (0.58) | MAOAMAOBFTOKDM4EALDH1A1 | |
| SCHEMBL4951315 | 0.78 | FTO (0.53) | MAOAMAOBFTOKDM4EACHE | |
| SCHEMBL31292049 | 0.78 | FTO (0.53) | MAOAMAOBFTOKDM4EACHE | |
| SCHEMBL3681299 | 0.76 | FTO (0.61) | MAOAMAOBFTOMAPTKDM4E | |
| SCHEMBL13665731 | 0.76 | MAOA (0.53) | MAOAMAOBFTOKDM4EACHE | |
| SCHEMBL1094182 | 0.76 | MAOA (0.59) | MAOAMAOBFTOKDM4EACHE | |
| SCHEMBL21303291 | 0.76 | MAOA (0.53) | MAOAMAOBFTOKDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103739617-B | Isoxazole norcantharidin derivative and preparation method thereof and application | SHAOXING UNIVERSITY (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-103554123-B | Containing chromone structure pyrazoles norcantharidin derivative and preparation method thereof and application | SHAOXING UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-103739617-A | Isoxazole norcantharidin derivative, and preparation method and application thereof | UNIV SHAOXING | 2014-04-23 | — | — | CN | claimed |
| CN-103554123-A | Chromone structure-containing pyrazole norcantharidin derivatives, and preparation method and application thereof | UNIV SHAOXING | 2014-02-05 | — | — | CN | claimed |
| EP-4680612-A1 | CHEMICAL COMPOUNDS | AN2 Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| US-20260015341-A1 | PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | HINOVA PHARMACEUTICALS INC (CN) | 2026-01-15 | — | — | US | disclosed |
| EP-4611741-A1 | TARGETING ALLOSTERIC AND ORTHOSTERIC POCKETS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-4553075-A1 | PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024192309-A1 | CHEMICAL COMPOUNDS | REACTIVE BIOSCIENCES, INC. (US) | 2024-09-19 | — | — | WO | disclosed |
| WO-2024097721-A1 | TARGETING ALLOSTERIC AND ORTHOSTERIC POCKETS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2024-05-10 | — | — | WO | disclosed |
| CN-117551092-A | Chromone compound containing 5-sulfone-1, 3, 4-thiadiazole, preparation method and sterilization application thereof | 南京农业大学 | 2024-02-13 | — | — | CN | disclosed |
| WO-2024008122-A1 | PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 海创药业股份有限公司 | 2024-01-11 | — | — | WO | disclosed |
| US-7473783-B2 | Bicyclic pyrazolo protein kinase modulators | SGX PHARMACEUTICALS, INC. (US) | 2009-01-06 | — | — | US | disclosed |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-04 | — | — | US | disclosed |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-04 | — | — | US | disclosed |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-04 | — | — | US | disclosed |
| US-20080207715-A1 | Novel Inhibitors of Glutaminyl Cyclase | PROBIODRUG AG (DE) | 2008-08-28 | — | — | US | disclosed |
| WO-2008055950-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-05-15 | — | — | WO | disclosed |
| US-20060281711-A1 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2006-12-14 | — | — | US | disclosed |
| WO-2006124662-A1 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281711-A1 | IL-12 modulatory compounds | IL2, IL4, IL15 | MAOA 2199/4885MAOB 2302/4885FTO 4633/4885 |
| US-20260015341-A1 | PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | PIK3CA, PIK3R4, PIK3R1 | MAOA 4554/4885MAOB 4550/4885FTO 2334/4885 |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | CCNK, CDK3, CCNO | MAOA 4495/4885MAOB 3989/4885FTO 4883/4885 |
| US-20080207715-A1 | Novel Inhibitors of Glutaminyl Cyclase | GLS, GLS2, GLUL | MAOA 886/4885MAOB 599/4885FTO 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.