Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.72 |
| ▸ | MAOA | P21397 | 8/20 | 0.53 |
| ▸ | MAOB | P27338 | 8/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799642 | 0.84 | FTO (1.00) | FTOMAOAMAOBMAPTNPC1 | |
| SCHEMBL546240 | 0.84 | FTO (1.00) | FTOMAOAMAOBMAPTNPC1 | |
| Methylene Chloride SCHEMBL27891472 | 0.79 | FTO (0.89) | FTOMAOAMAOBCYP3A4HPGD | |
| SCHEMBL365385 | 0.78 | MAOA (0.58) | FTOMAOAMAOBACHEHPGD | |
| SCHEMBL3681299 | 0.76 | FTO (0.61) | FTOMAOAMAOBACHEMAPT | |
| SCHEMBL1094182 | 0.76 | MAOA (0.59) | FTOMAOAMAOBACHEDYRK1A | |
| SCHEMBL21303291 | 0.76 | MAOA (0.53) | FTOMAOAMAOBACHEDYRK1A | |
| SCHEMBL932337 | 0.76 | MAOA (0.59) | FTOMAOAMAOBACHEMAPT | |
| SCHEMBL321544 | 0.76 | MAOA (0.59) | FTOMAOAMAOBACHEDYRK1A | |
| SCHEMBL13665731 | 0.76 | MAOA (0.53) | FTOMAOAMAOBACHEDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192454-B1 | AZABICYCLO-AMINO-TRIAZINE COMPOUNDS FOR MODULATING SPLICING FOR THE TREATMENT OF NEUROLOGICAL DISEASES | SKYHAWK THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20250353855-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2025-11-20 | — | — | US | disclosed |
| US-20230020922-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-19 | — | — | US | disclosed |
| US-20210030022-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP ASSETS B.V. (NL) | 2021-02-04 | — | — | US | disclosed |
| WO-2016097345-A1 | LABELLED CHROMONE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |
| CN-102993147-B | 4-chromone and 4-chromanone compound and purposes | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2015-09-09 | — | — | CN | disclosed |
| CN-101486701-B | Chromanone compound and analogue and medical application thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-06-19 | — | — | CN | disclosed |
| CN-102993147-A | 4-chromone and 4-chromanone compounds and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-03-27 | — | — | CN | disclosed |
| CN-102977064-A | 4-chromone and 4-chromanone compounds and medical application thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-03-20 | — | — | CN | disclosed |
| CN-101486715-B | Novel oxazine compound and use for preventing platelet aggregation | UNIV SHENYANG PHARMACEUTICAL | 2013-01-23 | — | — | CN | disclosed |
| US-5919950-A | SYNTHESIS OF SQUARATE DYES | POLAROID CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |
| US-5627014-A | COMPOSITIONS FOR ABSORBERS OF HEAT WHILE COLORING | POLAROID CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| US-5607928-A | Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives | ZENECA LIMITED (GB) | 1997-03-04 | — | — | US | disclosed |
| EP-0695753-A1 | Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | disclosed |
| EP-0190015-B1 | NOVEL 4H-1-BENZOPYRAN-4-ONES AND THEIR SULPHUR CONTAINING ANALOGS | WARNER-LAMBERT COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4780478-A | Aminopropoxy-chromones useful as antidepressants | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 1988-10-25 | — | — | US | disclosed |
| US-4678787-A | PSYCHOSIS, SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0190015-A1 | Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs | WARNER-LAMBERT COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
| US-4508732-A | Basic ethers useful as antidepressant agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-02 | — | — | US | disclosed |
| US-4376123-A | Hexahydroazepinyloxy-chromones useful as antidepressants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210030022-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | KMO, FFAR3, ACOX3 | FTO 14/4885MAOA 344/4885MAOB 715/4885 |
| US-20230020922-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SNRPA1 | FTO 2943/4885MAOA 4459/4885MAOB 3954/4885 |
| US-20250353855-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HTT, HYPK, FH | FTO 4160/4885MAOA 122/4885MAOB 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.