Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 9/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.30 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215570 | 0.89 | KDM4C (0.40) | JMJD6ROCK1S1PR5 | |
| SCHEMBL3206278 | 0.84 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1JMJD6 | |
| SCHEMBL1850714 | 0.79 | KDM4E (0.49) | ALDH1A1L3MBTL1JMJD6ROCK1MAPT | |
| SCHEMBL3207187 | 0.78 | JMJD6 (0.33) | ALDH1A1L3MBTL1JMJD6 | |
| SCHEMBL1851577 | 0.77 | CYP2A6 (0.41) | S1PR5 | |
| SCHEMBL1850872 | 0.74 | KDM4C (0.49) | ROCK1S1PR5 | |
| SCHEMBL3206270 | 0.72 | KDM4C (0.40) | JMJD6S1PR5 | |
| SCHEMBL1851004 | 0.70 | KDM4E (0.48) | ALDH1A1L3MBTL1JMJD6ROCK1MAPT | |
| SCHEMBL3207183 | 0.68 | KDM4C (0.38) | ROCK1PFKFB4 | |
| SCHEMBL1848497 | 0.66 | HPGD (0.47) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | ALDH1A1 2005/4885L3MBTL1 3700/4885JMJD6 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.