Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.34 |
| ▸ | KDM4A | O75164 | 5/20 | 0.34 |
| ▸ | KDM5C | P41229 | 4/20 | 0.34 |
| ▸ | KDM4B | O94953 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 4/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 4/20 | 0.33 |
| ▸ | KDM6B | O15054 | 3/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PFKFB4 | Q16877 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.31 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207187 | 0.90 | JMJD6 (0.33) | HDAC1 | |
| SCHEMBL3206270 | 0.81 | KDM4C (0.40) | KDM4CKDM5BKDM4AKDM5CKDM4B | |
| SCHEMBL3215570 | 0.79 | KDM4C (0.40) | KDM4CKDM5BKDM4AKDM5CKDM4B | |
| SCHEMBL1851302 | 0.77 | KDM4E (0.46) | KDM4CKDM5BKDM5CKDM3AKDM6B | |
| SCHEMBL3212096 | 0.74 | JAK2 (0.32) | — | |
| SCHEMBL3206278 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL1856110 | 0.71 | KDM4C (0.51) | KDM4CROCK1 | |
| SCHEMBL3215577 | 0.68 | ALDH1A1 (0.37) | PFKFB4ROCK1 | |
| SCHEMBL1853064 | 0.68 | KDM4C (0.48) | KDM4CROCK1 | |
| SCHEMBL3198407 | 0.68 | KDM4E (0.45) | KDM4CKDM5BKDM5CKDM3AKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | KDM4C 2640/4885KDM5B 2095/4885KDM4A 1985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.