Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425164 | 0.76 | CYP1A2 (0.41) | KDM4EGAAL3MBTL1ACHEALDH1A1 | |
| SCHEMBL30664412 | 0.75 | ALDH1A1 (0.42) | KDM4EGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL15422481 | 0.75 | ALDH1A1 (0.42) | KDM4EGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL14001428 | 0.75 | ALDH1A1 (0.42) | KDM4EGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL14144361 | 0.74 | CYP1A2 (0.40) | KDM4EGAAL3MBTL1ACHEALDH1A1 | |
| SCHEMBL2847420 | 0.72 | CYP1A2 (0.38) | KDM4EGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL26634699 | 0.71 | CYP1A2 (0.47) | KDM4EGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL26199979 | 0.70 | — | — | |
| SCHEMBL10109864 | 0.68 | HNF4A (0.45) | KDM4EGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL11988006 | 0.68 | ALDH1A1 (0.35) | KDM4EGAAL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069684-A1 | ASSYMMETRIC HYDROGENERATION OF PROCHIRAL COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2010-03-18 | — | — | US | claimed |
| EP-2094624-A1 | ASSYMMETRIC HYDROGENERATION OF PROCHIRAL COMPOUNDS | DSMIP Assets B.V. (NL) | 2009-09-02 | — | — | EP | claimed |
| EP-1951677-B1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-02 | — | — | EP | claimed |
| WO-2008077610-A1 | ASSYMMETRIC HYDROGENERATION OF PROCHIRAL COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2008-07-03 | — | — | WO | claimed |
| WO-2018060512-A1 | PROCESS FOR PREPARING CHIRAL AMINES | PATHEON AUSTRIA GMBH & CO KG (AT) | 2018-04-05 | — | — | WO | disclosed |
| EP-3301087-A1 | PROCESS FOR PREPARING CHIRAL AMINES | DPx Fine Chemicals Austria GmbH & Co KG (AT) | 2018-04-04 | — | — | EP | disclosed |
| US-20100069684-A1 | ASSYMMETRIC HYDROGENERATION OF PROCHIRAL COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2010-03-18 | — | — | US | disclosed |
| EP-2094624-A1 | ASSYMMETRIC HYDROGENERATION OF PROCHIRAL COMPOUNDS | DSMIP Assets B.V. (NL) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008077610-A1 | ASSYMMETRIC HYDROGENERATION OF PROCHIRAL COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2008-07-03 | — | — | WO | disclosed |
| EP-1830958-A1 | PROCESS FOR TRANSITION METAL-CATALYZED ASYMMETRIC HYDROGENATION OF ACRYLIC ACID DERIVATIVES, AND A NOVEL CATALYST SYSTEM FOR ASYMMETRIC TRANSITION METAL CATALYSIS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006069617-A1 | PROCESS FOR TRANSITION METAL-CATALYZED ASYMMETRIC HYDROGENATION OF ACRYLIC ACID DERIVATIVES, AND A NOVEL CATALYST SYSTEM FOR ASYMMETRIC TRANSITION METAL CATALYSIS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2006-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069684-A1 | ASSYMMETRIC HYDROGENERATION OF PROCHIRAL COMPOUNDS | PDHB, ME1, PDHA1 | KDM4E 1268/4885GAA 3620/4885L3MBTL1 2465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.