Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153933 | 1.00 | TBXAS1 (0.40) | TBXAS1APPLMNATSHRNFKB1 | |
| SCHEMBL717246 | 1.00 | TBXAS1 (0.40) | TBXAS1APPLMNATSHRNFKB1 | |
| SCHEMBL21344 | 0.98 | APP (0.39) | TBXAS1APPLMNAEPHX2PTGS1 | |
| Ammonia Solution, Strong SCHEMBL828485 | 0.96 | APP (0.38) | TBXAS1APPLMNAEPHX2PTGS1 | |
| SCHEMBL11287302 | 0.96 | TBXAS1 (0.40) | TBXAS1APPLMNAEPHX2PTGS1 | |
| SCHEMBL22984 | 0.91 | APP (0.41) | TBXAS1APPLMNAPTGS1PDE4A | |
| SCHEMBL9574853 | 0.89 | APP (0.39) | TBXAS1APPLMNAPTGS1PDE4A | |
| Ammonia Solution, Strong SCHEMBL5050825 | 0.89 | APP (0.39) | TBXAS1APPLMNAPTGS1PDE4A | |
| SCHEMBL15646946 | 0.89 | APP (0.39) | TBXAS1APPLMNAPTGS1PDE4A | |
| SCHEMBL15859186 | 0.89 | APP (0.39) | TBXAS1APPLMNAPTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835675-B2 | Polymerizable phosphonic acid derivative and adhesive composition comprising the same | KABUSHIKI KAISHA SHOFU (JP) | 2014-09-16 | — | — | US | disclosed |
| US-20100069524-A1 | Single-Component dental composition containing silane coupling agent and acidic group-containing polymerizable monomer | KABUSHIKI KAISHA SHOFU | 2010-03-18 | — | — | US | disclosed |
| US-20090048426-A1 | POLYMERIZABLE PHOSPHONIC ACID DERIVATIVE AND ADHESIVE COMPOSITION COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069524-A1 | Single-Component dental composition containing silane coupling agent and acidic group-containing polymerizable monomer | CAD, ITGA1, CIB1 | TBXAS1 3713/4885APP 2211/4885LMNA 2065/4885 |
| US-20090048426-A1 | POLYMERIZABLE PHOSPHONIC ACID DERIVATIVE AND ADHESIVE COMPOSITION COMPRISING THE SAME | PTK2, ITGA1, ACTN1 | TBXAS1 2727/4885APP 3296/4885LMNA 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.