SCHEMBL3219302

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4170417	0.89	POLB (0.34)	EPHX2KMT2AALDH1A1TAS1R3TAS1R1
	SCHEMBL3223452	0.86	HSP90AA1 (0.46)	EPHX2KMT2AALDH1A1HSP90AA1MEN1
	SCHEMBL3219307	0.83	KMT2A (0.42)	EPHX2KMT2AALDH1A1HSP90AA1TAS1R3
	SCHEMBL3227781	0.81	KMT2A (0.41)	EPHX2KMT2AALDH1A1HSP90AA1TAS1R3
	SCHEMBL4251171	0.81	TAS1R3 (0.40)	EPHX2KMT2AALDH1A1HSP90AA1TAS1R3
	SCHEMBL3216075	0.80	THRB (0.36)	KMT2AALDH1A1MEN1KDM4EHPGD
	SCHEMBL3219860	0.79	THRB (0.39)	KMT2AALDH1A1MEN1KDM4E
	SCHEMBL3229441	0.79	POLB (0.50)	ALDH1A1POLBRAB9AKDM4EHPGD
	SCHEMBL3220483	0.78	KMT2A (0.45)	KMT2AALDH1A1MEN1TDP1POLB
	SCHEMBL4170419	0.78	POLB (0.41)	EPHX2KMT2AALDH1A1HSP90AA1TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.