Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 3/20 | 0.43 |
| ▸ | FBP1 | P09467 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214421 | 1.00 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL30483777 | 0.86 | FBP1 (0.41) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL2537636 | 0.80 | PRMT1 (0.58) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL30740811 | 0.80 | PRMT1 (0.58) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL29103652 | 0.80 | PRMT1 (0.58) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL2537633 | 0.80 | PRMT1 (0.58) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL3210719 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTMTNR1AMTNR1BNQO2 | |
| SCHEMBL3010462 | 0.77 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTMITFFBP1 | |
| SCHEMBL3010460 | 0.77 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTMITFFBP1 | |
| SCHEMBL31451378 | 0.75 | MTNR1A (0.44) | ALDH1A1LMNAMAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258173-B2 | Melatonin derivatives and their use as antioxidants | UNIVERSITY OF SUNDERLAND (GB) | 2012-09-04 | — | — | US | disclosed |
| US-20100063125-A1 | MELATONIN DERIVATIVES AND THEIR USE AS ANTIOXIDANTS | UNIVERSITY OF SUNDERLAND (GB) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063125-A1 | MELATONIN DERIVATIVES AND THEIR USE AS ANTIOXIDANTS | MTNR1A, MTNR1B, TXNRD2 | ALDH1A1 250/4885LMNA 2090/4885MAPT 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.