SCHEMBL3220143

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3230905	0.79	MEN1 (0.50)	ATMPTGS2PTGS1ALDH1A1MAPT
	SCHEMBL3223168	0.78	MAPT (0.56)	ATMPTGS2PTGS1ALDH1A1MAPT
	SCHEMBL10330357	0.78	HPGD (0.56)	ALOX5ALDH1A1MAPTGAAHTT
	SCHEMBL3210223	0.76	PTGS2 (0.40)	ATMALOX5PTGS2PTGS1ALDH1A1
	SCHEMBL7912386	0.75	MEN1 (0.52)	ALDH1A1MAPTTSHRGAACYP1A2
	SCHEMBL758323	0.75	ATM (0.66)	ATMPTGS2TSHRGAAL3MBTL1
	SCHEMBL24458113	0.72	NPC1 (0.65)	ATMPTGS2ALDH1A1MAPTGAA
	SCHEMBL15624757	0.69	ATM (0.59)	ATMPTGS2TSHRGAAL3MBTL1
	SCHEMBL27854375	0.69	ALDH1A1 (0.54)	ALDH1A1MAPTTSHRMAPK1GAA
	SCHEMBL2602390	0.68	PTGS2 (0.56)	ALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.