SCHEMBL3221291

SCHEMBL3221291

Cc1ccc2c(c1)c1c(n2C)C([Ti](C)(C)(NC(C)(C)C)[SiH](C)C)c2ccccc2-1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
NR1I2 O75469 1/20 0.31
AHR P35869 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3224020 0.87 MAPT (0.39) MEN1KMT2A
SCHEMBL3223482 0.75 MEN1 (0.32) MEN1KMT2A
SCHEMBL28436475 0.73 GPR3 (0.32) MEN1KMT2A
SCHEMBL26822553 0.73 MEN1 (0.35) MEN1NR1I2AHRKMT2A
SCHEMBL4372185 0.72 BCHE (0.34) MEN1NR1I2AHRKMT2A
SCHEMBL7124338 0.70 MEN1 (0.39) MEN1NR1I2AHRKMT2A
SCHEMBL7636376 0.69 MEN1 (0.37) MEN1NR1I2AHRKMT2A
Hydrochloric Acid SCHEMBL3923993 0.68 MEN1 (0.36) MEN1NR1I2AHRKMT2A
SCHEMBL4375945 0.68 MEN1 (0.39) MEN1NR1I2AHRKMT2A
Hydrochloric Acid SCHEMBL7120127 0.68 MEN1 (0.36) MEN1NR1I2AHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799722-B2 Catalyst system for the polymerization of olefin BASELL POLYOLEFINE GMBH (DE) 2010-09-21 US disclosed
EP-1533324-B1 A ligand for a metallocene catalyst used to prepare propylene based polymers, and its preparation method BASELL POLYOLEFINE GMBH (DE) 2009-05-06 EP disclosed
US-20080281062-A1 Catalyst System for the Polymerization of Olefin BASELL POLYOLEFINE GMBH (DE) 2008-11-13 US disclosed
US-7365137-B2 Multistep process for the (co) polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2008-04-29 US disclosed
EP-1533324-A2 A ligand for a metallocene catalyst used to prepare propylene based polymers, and its preparation method Basell Polyolefine GmbH (DE) 2005-05-25 EP disclosed
EP-1159310-B1 PROCESS FOR PRODUCING SUBSTANTIALLY AMORPHOUS PROPYLENE-BASED POLYMERS BASELL POLYOLEFINE GMBH (DE) 2005-03-30 EP disclosed
US-20040242815-A1 Multistep process for the (co) polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2004-12-02 US disclosed
US-6730754-B2 COORDINATION POLYMERIZATION CATALYST BASELL POLYOLEFINE GMBH (DE) 2004-05-04 US disclosed
EP-1406969-A1 MULTISTEP PROCESS FOR THE (CO)POLYMERIZATION OF OLEFINS Basell Polyolefine GmbH (DE) 2004-04-14 EP disclosed
WO-2003008496-A1 MULTISTEP PROCESS FOR THE (CO)POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2003-01-30 WO disclosed
US-20020147286-A1 Process for producing substantially amorphous propylene-based polymers EQUISTAR CHEMICALS, LP 2002-10-10 US disclosed
EP-1159310-A1 PROCESS FOR PRODUCING SUBSTANTIALLY AMORPHOUS PROPYLENE-BASED POLYMERS Basell Technology Company B.V. (NL) 2001-12-05 EP disclosed
WO-2001053360-A1 PROCESS FOR PRODUCING SUBSTANTIALLY AMORPHOUS PROPYLENE-BASED POLYMERS BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242815-A1 Multistep process for the (co) polymerization of olefins CCNT1, TST, SOAT1 MEN1 1242/4885NR1I2 2747/4885AHR 2141/4885
US-20020147286-A1 Process for producing substantially amorphous propylene-based polymers GRB7, CHRM1, CPNE4 MEN1 2468/4885NR1I2 539/4885AHR 1365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.