Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025439 | 0.88 | KCNH3 (0.49) | RHOAKCNH3SMN1; SMN2RAB9AMAPT | |
| SCHEMBL3219439 | 0.85 | DHFR (0.43) | KCNH3MAPTMAPK1 | |
| SCHEMBL3226446 | 0.82 | KCNH3 (0.40) | KCNH3MAPTHTTMAPK1 | |
| SCHEMBL3226440 | 0.82 | KCNH3 (0.40) | KCNH3MAPTHTTMAPK1 | |
| SCHEMBL3226231 | 0.82 | MAPT (0.46) | POLBSMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL3230531 | 0.81 | L3MBTL1 (0.43) | KCNH3SMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL3209031 | 0.81 | MKNK1 (0.43) | KCNH3MAPTNAMPT | |
| SCHEMBL3219351 | 0.78 | RAB9A (0.42) | RAB9AMAPTKDM4EHTTNPC1 | |
| SCHEMBL3217193 | 0.78 | AURKA (0.39) | POLBRXFP1KCNH3SMN1; SMN2RAB9A | |
| SCHEMBL3218461 | 0.76 | RAB9A (0.47) | POLBSMN1; SMN2RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2010-02-25 | — | — | US | claimed |
| US-20080253978-A1 | Derivatives of Pyrrolyltriazine Together with Methods for Obtaining Them and Their Use as Protecting Agents Uv Radiation | ISDIN, S.A. (ES) | 2008-10-16 | — | — | US | claimed |
| WO-2008083975-A1 | LIGHT-STABILIZED COMPOSITION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | claimed |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2010-02-25 | — | — | US | disclosed |
| US-20080253978-A1 | Derivatives of Pyrrolyltriazine Together with Methods for Obtaining Them and Their Use as Protecting Agents Uv Radiation | ISDIN, S.A. (ES) | 2008-10-16 | — | — | US | disclosed |
| US-20080253978-A1 | Derivatives of Pyrrolyltriazine Together with Methods for Obtaining Them and Their Use as Protecting Agents Uv Radiation | ISDIN, S.A. (ES) | 2008-10-16 | — | — | US | disclosed |
| US-20080253978-A1 | Derivatives of Pyrrolyltriazine Together with Methods for Obtaining Them and Their Use as Protecting Agents Uv Radiation | ISDIN, S.A. (ES) | 2008-10-16 | — | — | US | disclosed |
| WO-2008083975-A1 | LIGHT-STABILIZED COMPOSITION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | disclosed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | UGT2B17, TACR2, UGT1A1 | MAPK13 3997/4885MAPK12 3536/4885MAPK11 3594/4885 |
| US-20080253978-A1 | Derivatives of Pyrrolyltriazine Together with Methods for Obtaining Them and Their Use as Protecting Agents Uv Radiation | UNG, TPMT, PPOX | MAPK13 4202/4885MAPK12 4605/4885MAPK11 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.