SCHEMBL3222443

SCHEMBL3222443

C=CCOCC(CO)OC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 5/20 0.67
PRKCE Q02156 2/20 0.67
PRKCQ Q04759 2/20 0.67
PRKCD Q05655 2/20 0.67
MAPT P10636 2/20 0.67
MAPK1 P28482 1/20 0.67
TSHR P16473 1/20 0.56
ALDH1A1 P00352 2/20 0.55
LMNA P02545 2/20 0.55
S1PR1 P21453 1/20 0.53
FAAH O00519 1/20 0.51
HPGD P15428 1/20 0.51
CNR1 P21554 1/20 0.51
CNR2 P34972 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11335400 0.87 ALDH1A1 (0.75) PRKCAPRKCEPRKCQPRKCDTSHR
SCHEMBL11328133 0.86 ALDH1A1 (0.72) PRKCAPRKCEPRKCQPRKCDTSHR
SCHEMBL13110571 0.85 MAPT (0.80) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL13110576 0.85 MAPT (0.80) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL13110574 0.85 MAPT (0.80) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL13110570 0.85 MAPT (0.80) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL13110786 0.85 MAPT (0.80) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL29411373 0.85 MAPT (0.80) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL17750135 0.84 TSHR (0.58) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL10902846 0.83 PRKCA (0.43) PRKCAPRKCEPRKCQPRKCDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198473-B2 Process for preparing organically modified siloxanes EVONIK GOLDSCHMIDT GMBH (DE) 2012-06-12 US disclosed
US-20100056818-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES EVONIK GOLDSCHMIDT GMBH (DE) 2010-03-04 US disclosed
US-7635581-B2 Process for preparing organically modified siloxanes GOLDSCHMIDT GMBH (DE) 2009-12-22 US disclosed
US-20070184006-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES GOLDSCHMIDT GMBH (DE) 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070184006-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES HSD17B12, CYP51A1, ESD PRKCA 4052/4885PRKCE 4183/4885PRKCQ 4385/4885
US-20100056818-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES HSD17B12, CYP51A1, ESD PRKCA 4052/4885PRKCE 4183/4885PRKCQ 4385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.