Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIP5K2 | O43314 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219718 | 1.00 | PPIP5K2 (0.40) | PPIP5K2EPHX1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3210082 | 0.92 | PPIP5K2 (0.43) | PPIP5K2EPHX1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL12678103 | 0.90 | SMN1; SMN2 (0.46) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL3206364 | 0.85 | EPHX1 (0.50) | PPIP5K2EPHX1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3210063 | 0.84 | EPHX1 (0.53) | PPIP5K2EPHX1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3220758 | 0.84 | EPHX1 (0.53) | PPIP5K2EPHX1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3220120 | 0.84 | EPHX1 (0.53) | PPIP5K2EPHX1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9186137 | 0.81 | ALDH1A1 (0.52) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL24793189 | 0.76 | SMN1; SMN2 (0.50) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL16359229 | 0.76 | EPHX1 (0.55) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120316208-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE THWART MYCOBACTERIAL GROWTH | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-12-13 | — | — | US | disclosed |
| US-8273778-B2 | Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-09-25 | — | — | US | disclosed |
| US-20100056586-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE THWART MYCOBACTERIAL GROWTH | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056586-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE THWART MYCOBACTERIAL GROWTH | UGDH, UGGT1, UMPS | PPIP5K2 853/4885EPHX1 2589/4885ALDH1A1 408/4885 |
| US-20120316208-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE THWART MYCOBACTERIAL GROWTH | UGDH, UGGT1, UMPS | PPIP5K2 853/4885EPHX1 2589/4885ALDH1A1 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.