Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3221433 | 1.00 | SMYD3 (0.44) | SMYD3CHEK1F10MAPK11MAPK14 | |
| SCHEMBL3211035 | 0.94 | SMYD3 (0.49) | SMYD3CHEK1F10MAPK11MAPK14 | |
| SCHEMBL13490569 | 0.94 | SMYD3 (0.49) | SMYD3CHEK1F10MAPK11MAPK14 | |
| SCHEMBL13490698 | 0.94 | SMYD3 (0.49) | SMYD3CHEK1F10MAPK11MAPK14 | |
| Hydrochloric Acid SCHEMBL3210407 | 0.93 | SMYD3 (0.48) | SMYD3CHEK1F10MAPK11MAPK14 | |
| Trifluoroacetic Acid SCHEMBL3210512 | 0.91 | HTR2B (0.43) | CHEK1HTR2BSMN1; SMN2CXCR6GID4 | |
| Trifluoroacetic Acid SCHEMBL3219974 | 0.87 | EPHX2 (0.47) | CHEK1HTR2BSMN1; SMN2CXCR6GID4 | |
| Trifluoroacetic Acid SCHEMBL3223613 | 0.86 | FOXO1 (0.45) | CHEK1HTR2BCXCR6 | |
| Trifluoroacetic Acid SCHEMBL3216470 | 0.86 | HTR2B (0.43) | CHEK1HTR2BSMN1; SMN2CXCR6GID4 | |
| Trifluoroacetic Acid SCHEMBL3218339 | 0.86 | CXCR6 (0.42) | CHEK1HTR2BSMN1; SMN2CXCR6GID4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | SMYD3 223/4885CHEK1 1651/4885F10 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.