Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR6 | O00574 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490686 | 0.94 | CXCR6 (0.46) | CXCR6HTR2BCHEK1GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3219974 | 0.88 | EPHX2 (0.47) | CXCR6HTR2BCHEK1GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3210512 | 0.88 | HTR2B (0.43) | CXCR6HTR2BCHEK1GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3210802 | 0.88 | RAB9A (0.55) | CXCR6HTR2BCHEK1 | |
| Trifluoroacetic Acid SCHEMBL3208139 | 0.87 | CHRM4 (0.43) | CXCR6HTR2BCHEK1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3216470 | 0.87 | HTR2B (0.43) | CXCR6HTR2BCHEK1GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3221433 | 0.86 | SMYD3 (0.44) | CXCR6HTR2BCHEK1GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3223330 | 0.86 | SMYD3 (0.44) | CXCR6HTR2BCHEK1GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3223613 | 0.85 | FOXO1 (0.45) | CXCR6HTR2BCHEK1PAX8 | |
| Trifluoroacetic Acid SCHEMBL3222205 | 0.85 | MLLT1 (0.54) | CXCR6HTR2BCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | CXCR6 3847/4885HTR2B 3456/4885CHEK1 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.