Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.47 |
| ▸ | METAP2 | P50579 | 8/20 | 0.40 |
| ▸ | METAP1 | P53582 | 7/20 | 0.40 |
| ▸ | LAP3 | P28838 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13688424 | 1.00 | GPR88 (0.47) | GPR88METAP2METAP1LAP3ANPEP | |
| Hydrochloric Acid SCHEMBL3207943 | 0.89 | GPR88 (0.39) | GPR88METAP2METAP1 | |
| SCHEMBL13770899 | 0.88 | METAP2 (0.42) | GPR88METAP2METAP1LAP3ANPEP | |
| SCHEMBL14401963 | 0.87 | ANPEP (0.42) | GPR88METAP2METAP1LAP3ANPEP | |
| Hydrochloric Acid SCHEMBL3224125 | 0.87 | GPR88 (0.43) | GPR88METAP2ATMAOC3 | |
| Hydrochloric Acid SCHEMBL3210982 | 0.87 | GPR88 (0.46) | GPR88METAP2METAP1LAP3ANPEP | |
| Hydrochloric Acid SCHEMBL3207851 | 0.86 | MMP2 (0.46) | GPR88METAP2METAP1LAP3ANPEP | |
| SCHEMBL13688833 | 0.84 | METAP2 (0.45) | GPR88METAP2METAP1ATMMEN1 | |
| SCHEMBL13688431 | 0.84 | METAP2 (0.45) | GPR88METAP2METAP1ATMMEN1 | |
| SCHEMBL13770906 | 0.84 | METAP2 (0.39) | GPR88METAP2METAP1LAP3ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130303547-A1 | HCV Protease Inhibitors and Uses Thereof | ABBVIE INC (US) | 2013-11-14 | — | — | US | disclosed |
| US-8497275-B2 | HCV protease inhibitors and uses thereof | ABBVIE INC. (US) | 2013-07-30 | — | — | US | disclosed |
| US-20100029686-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303547-A1 | HCV Protease Inhibitors and Uses Thereof | SERPINB1, PEPD, PREP | GPR88 4090/4885METAP2 150/4885METAP1 51/4885 |
| US-20100029686-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | SERPINB1, PEPD, PREP | GPR88 4090/4885METAP2 150/4885METAP1 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.