Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 8/20 | 0.39 |
| ▸ | METAP1 | P53582 | 7/20 | 0.39 |
| ▸ | LAP3 | P28838 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770899 | 0.87 | METAP2 (0.42) | METAP2METAP1LAP3ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL3210982 | 0.86 | GPR88 (0.46) | METAP2METAP1LAP3ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL3207851 | 0.85 | MMP2 (0.46) | METAP2METAP1LAP3ANPEPRNPEP | |
| SCHEMBL13688424 | 0.84 | GPR88 (0.47) | METAP2METAP1LAP3ANPEPRNPEP | |
| SCHEMBL3223600 | 0.84 | GPR88 (0.47) | METAP2METAP1LAP3ANPEPRNPEP | |
| SCHEMBL13688417 | 0.82 | GPR139 (0.55) | GPR139MEN1KMT2AATM | |
| SCHEMBL10173854 | 0.81 | METAP2 (0.41) | METAP2METAP1LAP3ANPEPRNPEP | |
| SCHEMBL8352593 | 0.81 | NPC1 (0.42) | GPR88 | |
| SCHEMBL13707848 | 0.81 | CTSL (0.44) | METAP2METAP1LAP3ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL3215065 | 0.81 | GPR139 (0.54) | GPR139MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301486-B1 | IMIDAZOLIDINONES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORP (US) | 2009-07-01 | — | — | EP | disclosed |