Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5587823 | 0.71 | LMNA (0.50) | KDM4EALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL6706942 | 0.67 | MAOB (0.48) | KDM4EALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL30314538 | 0.66 | GABRA1 (0.56) | KDM4EALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL5142961 | 0.66 | GABRA1 (0.56) | KDM4EALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL3211602 | 0.65 | NCEH1 (0.41) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL31035414 | 0.65 | ESR1 (0.39) | ALDH1A1TP53CYP3A4MAPK1ACHE | |
| SCHEMBL20745897 | 0.64 | TRPA1 (0.44) | KDM4EALDH1A1LMNATP53CYP3A4 | |
| Methoxymethane SCHEMBL28772216 | 0.64 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL1509536 | 0.64 | ALOX15 (0.45) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL31035705 | 0.64 | CA1 (0.41) | KDM4EALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012812-A1 | BENZAZEPINES AND BENZAZOCINES AS SIGMA-RECEPTOR LIGANDES | Westfälische Wilhelms Universität Münster (DE) | 2010-02-04 | — | — | WO | disclosed |