Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13963514 | 1.00 | PLA2G2A (0.58) | PLA2G2APLA2G5SMN1; SMN2ACE2TP53 | |
| SCHEMBL13963513 | 0.87 | ALDH1A1 (0.50) | PLA2G2APLA2G5SMN1; SMN2ACE2FAAH | |
| SCHEMBL29233005 | 0.87 | PLA2G2A (0.58) | PLA2G2APLA2G5SMN1; SMN2ACE2TP53 | |
| SCHEMBL4023087 | 0.86 | SMN1; SMN2 (0.49) | PLA2G2APLA2G5SMN1; SMN2TP53PPARG | |
| SCHEMBL13963510 | 0.83 | FAAH (0.62) | SMN1; SMN2ACE2FAAHGPR84CA1 | |
| SCHEMBL28051018 | 0.83 | FAAH (0.62) | SMN1; SMN2ACE2FAAHGPR84CA1 | |
| SCHEMBL13963508 | 0.83 | FAAH (0.62) | SMN1; SMN2ACE2FAAHGPR84CA1 | |
| SCHEMBL13963509 | 0.83 | FAAH (0.62) | SMN1; SMN2ACE2FAAHGPR84CA1 | |
| SCHEMBL14524255 | 0.82 | SMN1; SMN2 (0.54) | PLA2G2APLA2G5SMN1; SMN2TP53PPARG | |
| SCHEMBL13963515 | 0.81 | MMP3 (0.55) | ACE2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100065492-A1 | Compositions And Methods For Separating Enantiomers | WATERS TECHNOLOGIES CORPORATION (US) | 2010-03-18 | — | — | US | disclosed |
| US-7628920-B2 | Compositions and methods for separating enantiomers | WATERS TECHNOLOGIES CORPORATION (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080237130-A1 | Compositions and Methods for Separating Enantiomers | WATERS INVESTMENTS LIMITED (US) | 2008-10-02 | — | — | US | disclosed |
| WO-2005099855-A1 | COMPOSITIONS AND METHODS FOR SEPARATING ENANTIOMERS | WATERS INVESTMENTS LIMITED (US) | 2005-10-27 | — | — | WO | disclosed |