Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12693730 | 0.84 | PRMT6 (0.55) | PRMT6CARM1ROCK2ROCK1PRKCI | |
| SCHEMBL14202576 | 0.84 | PRMT6 (0.57) | PRMT6CARM1PRKCIMEN1RAB9A | |
| SCHEMBL3236780 | 0.81 | PRMT6 (0.51) | PRMT6CARM1PRKCIMEN1RAB9A | |
| SCHEMBL14204501 | 0.81 | PRMT6 (0.54) | PRMT6CARM1PRKCIMEN1RAB9A | |
| SCHEMBL17046829 | 0.79 | PRMT6 (0.67) | PRMT6ROCK2ROCK1PRKCIEPHX2 | |
| SCHEMBL3225438 | 0.78 | ROCK2 (0.58) | ROCK2ROCK1 | |
| SCHEMBL2095023 | 0.78 | PRMT6 (0.54) | PRMT6CARM1PRKCIMEN1RAB9A | |
| SCHEMBL19655691 | 0.77 | PRMT6 (0.64) | PRMT6CARM1MEN1RAB9AKMT2A | |
| SCHEMBL11966092 | 0.76 | KDM4D (0.47) | PRMT6CARM1ROCK2ROCK1PRKCI | |
| SCHEMBL14204945 | 0.76 | KDM4D (0.47) | PRMT6CARM1ROCK2ROCK1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242142-B2 | Cyclohexylamines, phenylamines and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-14 | — | — | US | disclosed |
| WO-2010022159-A1 | CYCLOHEXYLAMINES, PHENYLAMINES AND USES THEREOF | BIOSYNERGO (KY) | 2010-02-25 | — | — | WO | disclosed |
| US-20100048637-A1 | CYCLOHEXYLAMINES, PHENYLAMINES AND USES THEREOF | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048637-A1 | CYCLOHEXYLAMINES, PHENYLAMINES AND USES THEREOF | SMO, HNMT, INMT | PRMT6 80/4885CARM1 33/4885ROCK2 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.