Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326629 | 0.84 | TLR7 (0.40) | HSD17B10ALOX15MAPK1TP53KDM1A | |
| SCHEMBL23599062 | 0.83 | KDM1A (0.48) | HSD17B10ALOX15MAPK1TP53KDM1A | |
| SCHEMBL28726696 | 0.81 | NPC1 (0.49) | MAPK1NOS3NOS2MAPKAPK2CDK1 | |
| SCHEMBL5685446 | 0.81 | NOS3 (0.50) | MAPK1KDM1APOLBNOS3NOS2 | |
| SCHEMBL972297 | 0.80 | HSD11B1 (0.45) | MAPK1NOS3NOS2MAPKAPK2GSK3A | |
| SCHEMBL321539 | 0.79 | TLR7 (0.39) | HSD17B10ALOX15MAPK1TP53POLB | |
| SCHEMBL15674606 | 0.78 | TOP2A (0.44) | HSD17B10ALOX15KDM1ANOS3NOS2 | |
| SCHEMBL810884 | 0.78 | NOS3 (0.61) | MAPK1NOS3NOS2ALDH1A1TSHR | |
| SCHEMBL1968501 | 0.77 | BCAT2 (0.46) | NOS3NOS2KDM4ECNR2 | |
| SCHEMBL1690539 | 0.77 | TGFBR1 (0.39) | NOS3NOS2TLR7CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574510-B | Pyrimidine as herbicide Oxyphenyl derivatives | FMC 公司 | 2025-03-07 | — | — | CN | disclosed |
| US-11447476-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION (US) | 2022-09-20 | — | — | US | disclosed |
| US-20200270238-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2020-08-27 | — | — | US | disclosed |
| CN-111574510-A | Pyrimidinyloxybenzene derivatives as herbicides | FMC 公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-105916849-B | Pyrimidinyloxybenzene derivatives as herbicides | FMC公司 | 2020-07-07 | — | — | CN | disclosed |
| US-10654840-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190084972-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2019-03-21 | — | — | US | disclosed |
| EP-3094631-B1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2019-01-09 | — | — | EP | disclosed |
| US-10131652-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION | 2018-11-20 | — | — | US | disclosed |
| EP-3094631-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2016-11-23 | — | — | EP | disclosed |
| US-20160333000-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2016-11-17 | — | — | US | disclosed |
| WO-2015108779-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-23 | — | — | WO | disclosed |
| EP-2590951-B1 | BENZENESULFONAMIDES USEFUL AS SODIUM CHANNEL INHIBITORS | PFIZER LTD (GB) | 2015-01-07 | — | — | EP | disclosed |
| US-8772293-B2 | Chemical compounds | PFIZER LIMITED (GB) | 2014-07-08 | — | — | US | disclosed |
| EP-2590951-A1 | BENZENESULFONAMIDES USEFUL AS SODIUM CHANNEL INHIBITORS | Pfizer Limited (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004743-A1 | BENZENESULFONAMIDES USEFUL AS SODIUM CHANNEL INHIBITORS | PFIZER LIMITED (GB) | 2012-01-12 | — | — | WO | disclosed |
| US-20120010182-A1 | Chemical Compounds | ICAGEN INC. (US) | 2012-01-12 | — | — | US | disclosed |
| US-5783522-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10131652-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | HSD17B10 3209/4885ALOX15 1839/4885MAPK1 2992/4885 |
| US-10654840-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | HSD17B10 3209/4885ALOX15 1839/4885MAPK1 2992/4885 |
| US-20200270238-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | HSD17B10 3209/4885ALOX15 1839/4885MAPK1 2992/4885 |
| US-20120010182-A1 | Chemical Compounds | SCN1A, SCN1B, CACNA1E | HSD17B10 3885/4885ALOX15 3773/4885MAPK1 280/4885 |
| US-20160333000-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | HSD17B10 3209/4885ALOX15 1839/4885MAPK1 2992/4885 |
| US-11447476-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | HSD17B10 3209/4885ALOX15 1839/4885MAPK1 2992/4885 |
| US-20190084972-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | HSD17B10 3209/4885ALOX15 1839/4885MAPK1 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.