Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | WEE1 | P30291 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802505 | 0.85 | NR1H4 (0.53) | CA2PDE4BPDE4DCNR1KDM4E | |
| SCHEMBL3225952 | 0.83 | MAPT (0.40) | CNR1NPSR1KDM4EHTT | |
| SCHEMBL27463865 | 0.79 | MAPT (0.58) | CA2PDE4BNPSR1KDM4ETHRB | |
| SCHEMBL1579077 | 0.77 | SHMT1 (0.47) | CNR1CNR2HTT | |
| SCHEMBL625849 | 0.77 | ALDH1A1 (0.47) | CA2 | |
| SCHEMBL3340425 | 0.76 | CA2 (0.46) | CA2HTT | |
| SCHEMBL799654 | 0.76 | CA2 (0.64) | CA2 | |
| Hydrochloric Acid SCHEMBL3341453 | 0.74 | IDO1 (0.45) | CA2HTT | |
| Hydrochloric Acid SCHEMBL8185829 | 0.74 | CA2 (0.61) | CA2 | |
| Hydrochloric Acid SCHEMBL3818358 | 0.74 | CA2 (0.61) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010380-A1 | POTASSIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-01-28 | — | — | WO | disclosed |