Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802505 | 0.85 | NR1H4 (0.53) | NR1H4ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL3225959 | 0.83 | CA2 (0.47) | HTTCNR1NPSR1KDM4E | |
| SCHEMBL1579077 | 0.77 | SHMT1 (0.47) | MAPTNR1H4ALDH1A1MEN1KMT2A | |
| SCHEMBL3644216 | 0.76 | LMNA (0.55) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5465427 | 0.72 | PDE4B (0.53) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL9851152 | 0.70 | ALDH1A1 (0.46) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1686395 | 0.68 | TSHR (0.57) | MAPTALDH1A1GAAMEN1KMT2A | |
| Acetic Acid SCHEMBL1446325 | 0.68 | MAPT (0.59) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL31324192 | 0.68 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL31324190 | 0.68 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010380-A1 | POTASSIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-01-28 | — | — | WO | disclosed |