Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11721312 | 0.82 | DPP4 (0.47) | LMNAMAPK1TSHRCYP2D6SRC | |
| SCHEMBL13070538 | 0.81 | LMNA (0.50) | LMNAMAPK1TSHRKDM4EADRA2A | |
| SCHEMBL23337668 | 0.81 | LMNA (0.50) | LMNAMAPK1TSHRKDM4EADRA2A | |
| SCHEMBL26067052 | 0.77 | — | — | |
| SCHEMBL2336389 | 0.77 | — | — | |
| SCHEMBL9023354 | 0.72 | TAAR1 (0.42) | LMNATSHRKDM4EADRA2AADRA2C | |
| SCHEMBL19984820 | 0.72 | LMNA (0.44) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL4608564 | 0.72 | LMNA (0.52) | LMNAMAPK1TSHRKDM4EADRA2A | |
| SCHEMBL807041 | 0.72 | TAAR1 (0.44) | LMNATSHRKDM4EADRA2AADRA2C | |
| SCHEMBL2043473 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012812-A1 | BENZAZEPINES AND BENZAZOCINES AS SIGMA-RECEPTOR LIGANDES | Westfälische Wilhelms Universität Münster (DE) | 2010-02-04 | — | — | WO | disclosed |