Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311361 | 0.85 | IMPDH2 (0.41) | IMPDH2IMPDH1DRD2DRD3PNMT | |
| SCHEMBL20364829 | 0.78 | IMPDH2 (0.39) | IMPDH2IMPDH1DRD2DRD3PNMT | |
| SCHEMBL31352953 | 0.78 | IMPDH2 (0.39) | IMPDH2IMPDH1DRD2DRD3PNMT | |
| SCHEMBL17672451 | 0.75 | ALDH1A1 (0.40) | IMPDH2IMPDH1DRD2DRD3PNMT | |
| SCHEMBL1794400 | 0.75 | VCAM1 (0.46) | IMPDH2IMPDH1DRD2DRD3PNMT | |
| SCHEMBL23977435 | 0.75 | CA12 (0.43) | IMPDH2IMPDH1DRD2DRD3PNMT | |
| SCHEMBL2713742 | 0.75 | MPO (0.38) | IMPDH2IMPDH1DRD2DRD3PNMT | |
| SCHEMBL16620846 | 0.75 | FFAR1 (0.44) | IMPDH2IMPDH1DRD2DRD3PNMT | |
| SCHEMBL3032751 | 0.74 | CYP2A6 (0.46) | IMPDH2IMPDH1CYP2A6CA2ALDH1A1 | |
| SCHEMBL5642351 | 0.71 | IMPDH2 (0.41) | IMPDH2IMPDH1DRD2DRD3PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | CHRM1, PRDX1, CHRM2 | IMPDH2 1831/4885IMPDH1 1248/4885DRD2 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.