SCHEMBL322814

SCHEMBL322814

CCCCCCCCCCCCCCCCOOCCCCCCCCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.57
TSHR P16473 1/20 0.57
MEN1 O00255 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
MAPT P10636 1/20 0.48
CA1 P00915 8/20 0.46
CA2 P00918 8/20 0.46
CA9 Q16790 7/20 0.46
LPAR3 Q9UBY5 6/20 0.46
LPAR2 Q9HBW0 5/20 0.46
CA12 O43570 3/20 0.46
CA7 P43166 3/20 0.46
CA14 Q9ULX7 3/20 0.46
LPAR1 Q92633 2/20 0.46
CA3 P07451 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA5A P35218 2/20 0.46
CA5B Q9Y2D0 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3826183 1.00 THRB (0.57) THRBTSHRMEN1HTTKMT2A
SCHEMBL10581038 1.00 THRB (0.57) THRBTSHRMEN1HTTKMT2A
SCHEMBL22957 1.00 THRB (0.57) THRBTSHRMEN1HTTKMT2A
SCHEMBL2119344 1.00 THRB (0.57) THRBTSHRMEN1HTTKMT2A
SCHEMBL21218973 1.00 THRB (0.57) THRBTSHRMEN1HTTKMT2A
SCHEMBL1067348 1.00 THRB (0.57) THRBTSHRMEN1HTTKMT2A
SCHEMBL6827456 1.00 THRB (0.57) THRBTSHRMEN1HTTKMT2A
SCHEMBL10491770 1.00 THRB (0.57) THRBTSHRMEN1HTTKMT2A
SCHEMBL4162714 1.00 THRB (0.57) THRBTSHRMEN1HTTKMT2A
SCHEMBL8394850 1.00 THRB (0.57) THRBTSHRMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8216609-B2 Release dosage form comprising of a high solubility active ingredient, which utilizes dual retard technique to effectively reduce the quantity of release controlling agents; a process for preparing the dosage form. TORRENT PHARMACEUTICALS LIMITED (IN) 2012-07-10 US claimed
EP-1558220-B1 ORAL COMPOSITIONS FOR TREATMENT OF DIABETES WOCKHARDT LTD (IN) 2010-02-10 EP claimed
US-20240041775-A1 NEW MODIFIED RELEASE ORAL CONTRACEPTIVE COMPOSITION CHEMO RESEARCH, S.L. (ES) 2024-02-08 US disclosed
EP-4248938-A1 FLEXIBLE AND SOLID MAKE-UP PRODUCT, AND A SWATCH OF MAKE-UP PRODUCTS Chromavis S.p.A. (IT) 2023-09-27 EP disclosed
US-20230285266-A1 FLEXIBLE AND SOLID MAKE-UP PRODUCT, AND A SWATCH OF MAKE-UP PRODUCTS CHROMAVIS SPA (IT) 2023-09-14 US disclosed
EP-4196098-A1 NEW MODIFIED RELEASE ORAL CONTRACEPTIVE COMPOSITION Chemo Research, S.L. (ES) 2023-06-21 EP disclosed
WO-2022034209-A1 NEW MODIFIED RELEASE ORAL CONTRACEPTIVE COMPOSITION CHEMO RESEARCH, S.L. (ES) 2022-02-17 WO disclosed
EP-3954364-A1 NEW MODIFIED RELEASE ORAL CONTRACEPTIVE COMPOSITION Chemo Research, S.L. (ES) 2022-02-16 EP disclosed
WO-2020054590-A1 WATER-IN-OIL EMULSION COSMETIC COMPOSITION 株式会社 資生堂 2020-03-19 WO disclosed
EP-2352494-B1 NOVEL AND POTENT TAPENTADOL DOSAGE FORMS GRUENENTHAL GMBH (DE) 2019-10-09 EP disclosed
US-20170216212-A1 TAPENTADOL COMPOSITIONS GRUENENTHAL GMBH (DE) 2017-08-03 US disclosed
US-20080026054-A1 Novel anelgesic combination NECTID INC. (US) 2008-01-31 US disclosed
US-20070219107-A1 Sheet-Like Body Cleaning Material KAO CORPORATION (JP) 2007-09-20 US disclosed
US-20070172525-A1 Anti-diabetic combinations NECTID, INC. 2007-07-26 US disclosed
EP-1558220-A4 ORAL COMPOSITIONS FOR TREATMENT OF DISEASES WOCKHARDT LTD (IN) 2006-07-12 EP disclosed
US-20060134206-A1 Oral compositions for treatment of diseases WOCKHARDT LIMITED (IN) 2006-06-22 US disclosed
US-7056952-B1 for example, 3'-hydroxy-dihydrodaidzein, 5-hydroxy-O-demethylangolesin; for treating hormone dependent conditions and other diseases and disorders; anticarcinogenic agents G.J. CONSULTANTS PTY. LTD. (AU) 2006-06-06 US disclosed
EP-1558220-A1 ORAL COMPOSITIONS FOR TREATMENT OF DISEASES Wockhardt Limited (IN) 2005-08-03 EP disclosed
WO-2005009412-A1 ORAL COMPOSITIONS FOR TREATMENT OF DISEASES WOCKHARDT LIMITED (IN) 2005-02-03 WO disclosed
US-4405736-A 2,2,6,6-Tetramethyl-4-piperidyl spiro aliphatic ethers and stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170216212-A1 TAPENTADOL COMPOSITIONS GABRQ, GABRB3, GABRB2 THRB 1182/4885TSHR 2160/4885MEN1 4736/4885
US-20080026054-A1 Novel anelgesic combination OPRD1, OPRL1, NSD2 THRB 3340/4885TSHR 3692/4885MEN1 4725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.