Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 4/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18489379 | 0.82 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL18489377 | 0.82 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL16510230 | 0.79 | NNMT (0.42) | NNMTKMT2AMEN1CHRNA7POLB | |
| SCHEMBL24322112 | 0.79 | SMN1; SMN2 (0.45) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL29515045 | 0.79 | SMN1; SMN2 (0.45) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL5738845 | 0.76 | PTGS1 (0.35) | ALDH1A1 | |
| SCHEMBL10328715 | 0.76 | MAPK1 (0.50) | KDM4EMAPTALDH1A1 | |
| SCHEMBL18489349 | 0.76 | MAPK1 (0.50) | KDM4EMAPTALDH1A1 | |
| SCHEMBL30328009 | 0.75 | TRPV4 (0.40) | KCNH2PIK3CA | |
| SCHEMBL2609318 | 0.75 | OXTR (0.46) | NNMTKMT2AMEN1CHRNA7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010186-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |