Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.42 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360670 | 0.84 | ALDH1A1 (0.32) | ALDH1A1TDP1TSHRALOX15SMN1; SMN2 | |
| SCHEMBL16719736 | 0.83 | ALDH1A1 (0.31) | ALDH1A1TDP1TSHRALOX15SMN1; SMN2 | |
| SCHEMBL225599 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRALOX15SMN1; SMN2 | |
| SCHEMBL677730 | 0.78 | CA2 (0.33) | ALDH1A1TDP1TSHRALOX15SMN1; SMN2 | |
| SCHEMBL16720063 | 0.78 | HSP90AA1 (0.34) | — | |
| SCHEMBL1519797 | 0.77 | AR (0.32) | — | |
| SCHEMBL29084727 | 0.76 | CA2 (0.32) | ALDH1A1TDP1TSHRCA2 | |
| SCHEMBL6918917 | 0.74 | GABRA1 (0.35) | ALDH1A1TDP1TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL3693116 | 0.73 | CA2 (0.30) | CA2 | |
| SCHEMBL3693169 | 0.73 | CA2 (0.30) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585628-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2022-06-03 | — | — | CN | disclosed |
| US-9856914-B2 | Joint bearing lubricant system | THE BOEING COMPANY (US) | 2018-01-02 | — | — | US | disclosed |
| CN-106163517-A | Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases | 沃泰克斯药物股份有限公司 | 2016-11-23 | — | — | CN | disclosed |
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| US-20150369285-A1 | JOINT BEARING LUBRICANT SYSTEM | THE BOEING COMPANY | 2015-12-24 | — | — | US | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |
| CN-104470518-A | Pharmaceutical compositions and their administration | VERTEX PHARMA | 2015-03-25 | — | — | CN | disclosed |
| CN-101384172-B | Solid forms of N- [2, 4-bis (1, 1-dimethylethyl) -5-hydroxyphenyl ] -1, 4-dihydro-4-oxoquinoline-3-carboxamide | VERTEX PHARMA | 2014-05-07 | — | — | CN | disclosed |
| EP-1625193-B1 | BORATE ESTER LUBRICANT ADDITIVES | BASF SE (DE) | 2010-07-28 | — | — | EP | disclosed |
| CN-101522415-A | Laminate comprising polycarbonate resin | MGC FILSHEET CO LTD (JP) | 2009-09-02 | — | — | CN | disclosed |
| US-7291581-B2 | Borate ester lubricant additives | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-11-06 | — | — | US | disclosed |
| US-20040235681-A1 | Borate ester lubricant additives | CIBA SPECIALTY CHEMICALS CORP. | 2004-11-25 | — | — | US | disclosed |
| US-6605618-B2 | Antidiabetic agents; hypoglycemic agents; anticholesterol agents; side effect reduction | WYETH | 2003-08-12 | — | — | US | disclosed |
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | WYETH (US) | 2003-01-23 | — | — | US | disclosed |
| US-6451814-B1 | SUBSTITUTED 4-((4-AMINO-5-HYDROXYPHENYL)-OXY-)PIPERIDINE ANALOGS; METABOLIC DISORDERS; ANTIDIABETIC AGENTS; ATHERO-SCLEROSIS, GASTROINTESTINAL DISORDERS, GLAUCOMA, NEUROGENETIC INFLAMMATION, OCULAR HYPERTENSION AND FREQUENT URINATION | WYETH | 2002-09-17 | — | — | US | disclosed |
| US-20020028832-A1 | Heterocyclic beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | ALDH1A1 725/4885TDP1 3384/4885TSHR 603/4885 |
| US-20040235681-A1 | Borate ester lubricant additives | GRK1, BRSK1, EBPL | ALDH1A1 1625/4885TDP1 2684/4885TSHR 2188/4885 |
| US-20020028832-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | ALDH1A1 524/4885TDP1 2707/4885TSHR 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.