Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TNF | P01375 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405552 | 0.83 | KAT2B (0.43) | ALDH1A1KDM4ETNFKAT2BCNR2 | |
| SCHEMBL3214955 | 0.83 | KAT2B (0.43) | ALDH1A1KDM4ETNFKAT2B | |
| SCHEMBL11006782 | 0.82 | TP53 (0.58) | ALDH1A1KDM4ECREBBPRAB9A | |
| SCHEMBL3403616 | 0.82 | MTNR1A (0.46) | ALDH1A1TNFKAT2BRAB9AGAA | |
| SCHEMBL11514777 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KDM4ETNFCREBBPCXCR3 | |
| SCHEMBL3226989 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4ECA12BRD4BRPF1 | |
| SCHEMBL3227880 | 0.79 | KDM4E (0.49) | ALDH1A1KDM4ETNFCREBBPCXCR3 | |
| SCHEMBL6701625 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4ECREBBPCNR2 | |
| SCHEMBL15622413 | 0.78 | KDM4E (0.68) | ALDH1A1KDM4ECREBBPCXCR3CNR2 | |
| SCHEMBL1128275 | 0.78 | FNTA (0.68) | ALDH1A1KDM4ETNFCREBBPCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | NRDC, NACA, NAA50 | ALDH1A1 4233/4885KDM4E 3723/4885TNF 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.