Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 3/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405552 | 0.85 | KAT2B (0.43) | KAT2BALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL3403616 | 0.84 | MTNR1A (0.46) | KAT2BALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3229548 | 0.83 | ALDH1A1 (0.51) | KAT2BALDH1A1KDM4ETNF | |
| SCHEMBL3231703 | 0.82 | LMNA (0.43) | KAT2BALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL3218538 | 0.81 | KDM4E (0.46) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL17580370 | 0.80 | KDM4E (0.43) | SMN1; SMN2LMNAKDM4EMAPK14 | |
| SCHEMBL28779597 | 0.79 | HDAC1 (0.43) | KAT2BALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL3229333 | 0.78 | L3MBTL1 (0.44) | KAT2BALDH1A1FAAHHK1SMN1; SMN2 | |
| SCHEMBL30448661 | 0.76 | HDAC1 (0.43) | KAT2BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3227880 | 0.76 | KDM4E (0.49) | ALDH1A1LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | NRDC, NACA, NAA50 | KAT2B 1406/4885ALDH1A1 4233/4885FAAH 2915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.