SCHEMBL3230351

SCHEMBL3230351

CC(C)[C@H](NN1CCCC1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
CTSL P07711 1/20 0.36
CTSB P07858 1/20 0.36
CTSK P43235 1/20 0.36
HTT P42858 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
DPP4 P27487 1/20 0.34
MMP2 P08253 2/20 0.33
MMP3 P08254 2/20 0.33
MMP13 P45452 2/20 0.33
ADAMTS4 O75173 1/20 0.33
MMP1 P03956 1/20 0.33
MMP7 P09237 1/20 0.33
MMP9 P14780 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28628583 1.00 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2CTSLCTSBCTSK
SCHEMBL385712 0.78 L3MBTL1 (0.36) ALDH1A1SMN1; SMN2HTTGAAL3MBTL1
SCHEMBL385711 0.78 L3MBTL1 (0.36) ALDH1A1SMN1; SMN2HTTGAAL3MBTL1
SCHEMBL383047 0.77 L3MBTL1 (0.39) ALDH1A1HTTLMNAGAAL3MBTL1
SCHEMBL383046 0.77 L3MBTL1 (0.39) ALDH1A1HTTLMNAGAAL3MBTL1
Alanine SCHEMBL4954723 0.72 LTA4H (0.35) HTTL3MBTL1DPP4RAB9A
SCHEMBL31506885 0.71 HTT (0.38) ALDH1A1SMN1; SMN2HTTLMNAGAA
SCHEMBL7339055 0.71 SMN1; SMN2 (0.45) ALDH1A1SMN1; SMN2HTTGAANPSR1
SCHEMBL7339063 0.71 SMN1; SMN2 (0.45) ALDH1A1SMN1; SMN2HTTGAANPSR1
SCHEMBL676508 0.70 L3MBTL1 (0.35) ALDH1A1GAAL3MBTL1MMP2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010011325-A2 SYNTHESIS AND UTILIZATION OF SMALL MOLECULES FOR THE TREATMENT OF INFLAMMATION ASSOCIATED WITH INTERLEUKIN-1 SIGNALING THE SCRIPPS RESEARCH INSTITUTE (US) 2010-01-28 WO disclosed