Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 6/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3987570 | 0.98 | BRPF1 (0.48) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL27923254 | 0.78 | RPS6KA5 (0.44) | RPS6KA5KDM4EMAPTMETRPS6KA4 | |
| SCHEMBL13952491 | 0.78 | POLB (0.44) | FGFR1KDM4EMAPTCDK2SMN1; SMN2 | |
| SCHEMBL28014515 | 0.77 | RPS6KA5 (0.47) | RPS6KA5KDM4EMAPTMETRPS6KA4 | |
| SCHEMBL28026163 | 0.77 | RPS6KA5 (0.43) | RPS6KA5KDM4EMAPTMETRPS6KA4 | |
| SCHEMBL3515136 | 0.77 | DAO (0.47) | RPS6KA5KDM4EMAPTMETALDH1A1 | |
| SCHEMBL2206357 | 0.77 | SMN1; SMN2 (0.44) | RPS6KA5KDM4EMAPTMETRAPGEF4 | |
| SCHEMBL13767381 | 0.77 | ALDH1A1 (0.44) | RPS6KA5KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL29499648 | 0.76 | RPS6KA5 (0.42) | RPS6KA5FGFR1KDM4EMETRPS6KA4 | |
| SCHEMBL29580418 | 0.74 | KDM4E (0.51) | BRPF1CA12BRD4CA9KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-05-07 | — | — | US | claimed |
| US-20230271954-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES INC (US) | 2023-08-31 | — | — | US | claimed |
| EP-2029612-A1 | SUBSTITUTED 1-METHYL-1H-QUINOLIN-2-ONES AND 1-METHYL-1H-1,5-NAPHTHYRIDIN-2-ONES AS ANTIBACTERIALS | Glaxo Group Limited (GB) | 2009-03-04 | — | — | EP | claimed |
| WO-2008006648-A1 | SUBSTITUTED 1-METHYL-1H-QUINOLIN-2-ONES AND 1-METHYL-1H-1,5-NAPHTHYRIDIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2008-01-17 | — | — | WO | claimed |
| US-20250034141-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-01-30 | — | — | US | disclosed |
| EP-4081523-B1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2024-12-25 | — | — | EP | disclosed |
| US-12152027-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-11-26 | — | — | US | disclosed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | disclosed |
| US-11964973-B2 | Substituted bicyclic compounds useful as T cell activators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-04-23 | — | — | US | disclosed |
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |
| WO-2023122772-A1 | OXIME DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| US-20150144846-A1 | ORGANIC SEMICONDUCTOR | MERCK PATENT GMBH (DE) | 2015-05-28 | — | — | US | disclosed |
| US-20150144846-A1 | ORGANIC SEMICONDUCTOR | MERCK PATENT GMBH (DE) | 2015-05-28 | — | — | US | disclosed |
| EP-2702086-B1 | SEMICONDUCTOR MATERIALS BASED ON DIKETOPIPERIDINOPIPERIDINE COPOLYMERS | BASF SE (DE) | 2015-03-18 | — | — | EP | disclosed |
| US-8436127-B2 | Semiconductor materials based on diketopiperidinopiperidine copolymers | BASF SE (DE) | 2013-05-07 | — | — | US | disclosed |
| WO-2012146574-A1 | SEMICONDUCTOR MATERIALS BASED ON DIKETOPIPERIDINOPIPERIDINE COPOLYMERS | BASF SE (DE) | 2012-11-01 | — | — | WO | disclosed |
| US-20120277404-A1 | SEMICONDUCTOR MATERIALS BASED ON DIKETOPIPERIDINOPIPERIDINE COPOLYMERS | BASF SE (DE) | 2012-11-01 | — | — | US | disclosed |
| US-20120277404-A1 | SEMICONDUCTOR MATERIALS BASED ON DIKETOPIPERIDINOPIPERIDINE COPOLYMERS | BASF SE (DE) | 2012-11-01 | — | — | US | disclosed |
| US-20100256124-A1 | Substituted 1-Methyl-1H-Quinolin-2-Ones And 1-Methyl-1H-1,5-Naphthyridin-2-Ones As Antibacterials | GLAXO GROUP LIMITED (GB) | 2010-10-07 | — | — | US | disclosed |
| WO-2010046388-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | ZC3HAV1, CCR1, CCR6 | BRPF1 2763/4885CA12 1079/4885BRD4 615/4885 |
| US-20230271954-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | DGKZ, DGKA, DGKG | BRPF1 3516/4885CA12 3068/4885BRD4 890/4885 |
| US-20250034141-A1 | HETEROCYCLIC COMPOUND | MALT1, SQSTM1, PPM1D | BRPF1 4016/4885CA12 1633/4885BRD4 2253/4885 |
| US-20100256124-A1 | Substituted 1-Methyl-1H-Quinolin-2-Ones And 1-Methyl-1H-1,5-Naphthyridin-2-Ones As Antibacterials | TOP1, TOP2A, NDC1 | BRPF1 1378/4885CA12 4778/4885BRD4 42/4885 |
| US-12152027-B2 | Heterocyclic compound | MALT1, SQSTM1, PPM1D | BRPF1 4016/4885CA12 1633/4885BRD4 2253/4885 |
| US-20150144846-A1 | ORGANIC SEMICONDUCTOR | OCIAD2, OCIAD1, DDT | BRPF1 3027/4885CA12 4511/4885BRD4 2116/4885 |
| US-11964973-B2 | Substituted bicyclic compounds useful as T cell activators | DGKA, DGKZ, DGKK | BRPF1 2177/4885CA12 3300/4885BRD4 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.