Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16996646 | 0.72 | MMP2 (0.65) | MMP2TDP1CYP1A2HRH4HRH3 | |
| SCHEMBL14123282 | 0.65 | HRH4 (0.51) | MMP2ALDH1A1RAB9AHRH4HRH3 | |
| SCHEMBL727185 | 0.64 | CYP1A2 (0.62) | MMP2TDP1CYP1A2HRH4HRH3 | |
| SCHEMBL7371310 | 0.64 | ALDH1A1 (0.50) | PNPPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7377500 | 0.63 | ALDH1A1 (0.49) | PNPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7714583 | 0.63 | PLA2G7 (0.61) | PNPPLA2G7 | |
| SCHEMBL16996658 | 0.62 | ALDH1A1 (0.66) | MMP2ALDH1A1CYP1A2KDM4ECYP2C19 | |
| SCHEMBL6272181 | 0.62 | MMP2 (0.51) | MMP2ALDH1A1CYP1A2HRH4HRH3 | |
| SCHEMBL28818109 | 0.62 | MMP2 (0.51) | MMP2ALDH1A1CYP1A2ADORA2AHRH4 | |
| SCHEMBL29167032 | 0.62 | MMP2 (0.51) | MMP2ALDH1A1CYP1A2ADORA2AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014798-A2 | PYRIMIDOTRIAZINEDIONES AND PYRIMIDOPYRIMIDINEDIONES AND METHODS OF USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-02-04 | — | — | WO | disclosed |