Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | ABL2 | P42684 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469695 | 1.00 | FBP1 (0.67) | FBP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6469694 | 1.00 | FBP1 (0.67) | FBP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6954094 | 0.84 | FBP1 (0.61) | FBP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL27957137 | 0.82 | FBP1 (0.69) | FBP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL27946453 | 0.82 | FBP1 (0.69) | FBP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL2746679 | 0.82 | FBP1 (0.69) | FBP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL9850705 | 0.82 | FBP1 (0.59) | FBP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL10664676 | 0.82 | FBP1 (0.69) | FBP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL2746675 | 0.82 | FBP1 (0.69) | FBP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL2746676 | 0.82 | FBP1 (0.69) | FBP1MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020155925-A1 | NITROALKYL QUINOXALINE OR DERIVATIVE THEREOF, AMINOALKYL QUINOXALINE OR DERIVATIVE THEREOF, AND SYNTHESIS METHOD THEREFOR | 上海交通大学 | 2020-08-06 | — | — | WO | claimed |
| WO-2020155925-A1 | NITROALKYL QUINOXALINE OR DERIVATIVE THEREOF, AMINOALKYL QUINOXALINE OR DERIVATIVE THEREOF, AND SYNTHESIS METHOD THEREFOR | 上海交通大学 | 2020-08-06 | — | — | WO | disclosed |
| CN-103497082-B | A kind of method preparing beta-nitrostyrene and derivative thereof | TAIZHOU UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-103497082-A | Method for preparing beta-nitrostyrolene and derivatives thereof | UNIV TAIZHOU | 2014-01-08 | — | — | CN | disclosed |
| US-20050101657-A1 | Pyrrole derivatives for preventing or treating cancer sensitive to hormones; administered with luteininzing hormone releasing hormone derivative | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |
| EP-0928790-B1 | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2003-03-05 | — | — | EP | disclosed |
| US-6344562-B1 | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. | 2002-02-05 | — | — | US | disclosed |
| US-20020010316-A1 | Thiazole derivatives | ALIG LEO (CH) | 2002-01-24 | — | — | US | disclosed |
| US-6320054-B1 | INHIBIT BINDING OF ADHESIVE PROTEINS TO THE SURFACE OF DIFFERENT TYPES F CELL AND ACCORDINGLY INFLUENCE CELL-CELL AND CELL-MATRIX INTERACTIONS. | HOFFMAN-LA ROCHE INC. | 2001-11-20 | — | — | US | disclosed |
| US-6100282-A | Thiazole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2000-08-08 | — | — | US | disclosed |
| EP-0928790-A1 | Thiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010316-A1 | Thiazole derivatives | VCAM1, SOST, TGFB1 | FBP1 2082/4885MAPT 86/4885MEN1 681/4885 |
| US-20050101657-A1 | Pyrrole derivatives for preventing or treating cancer sensitive to hormones; administered with luteininzing hormone releasing hormone derivative | SHBG, PRLHR, FSHR | FBP1 3072/4885MAPT 4864/4885MEN1 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.