Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16245538 | 0.89 | LMNA (0.71) | NPC1RAB9ALMNAGFERCYP3A4 | |
| SCHEMBL1936079 | 0.84 | LMNA (0.55) | NPC1RAB9ALMNAMETCYP3A4 | |
| SCHEMBL8758151 | 0.84 | MET (0.56) | NPC1RAB9ALMNAMETALDH1A1 | |
| SCHEMBL5703716 | 0.82 | LMNA (0.53) | NPC1RAB9ALMNACYP3A4TSHR | |
| SCHEMBL16244405 | 0.82 | LMNA (0.53) | NPC1RAB9ALMNAALDH1A1MAPK1 | |
| SCHEMBL16244411 | 0.82 | LMNA (0.53) | NPC1RAB9ALMNACYP3A4TSHR | |
| SCHEMBL15650450 | 0.82 | LMNA (0.53) | LMNAALDH1A1L3MBTL1MAOBCYP1A2 | |
| SCHEMBL6552773 | 0.82 | LMNA (0.53) | NPC1RAB9ALMNAMETCYP3A4 | |
| SCHEMBL30694096 | 0.82 | NPC1 (0.56) | NPC1RAB9AGFERMETCYP3A4 | |
| SCHEMBL2540602 | 0.82 | NPC1 (0.56) | NPC1RAB9ALMNAGFERMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117838875-A | Drug delivery system for local delivery of therapeutic agents and uses thereof | 上海椿安生物医药科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117586234-A | CDKL 3-targeted small molecule inhibitor HZ1 and derivative HZ1-X thereof | 盛韧 | 2024-02-23 | — | — | CN | disclosed |
| CN-115867319-B | Drug delivery system for local delivery of therapeutic agents and uses thereof | 上海椿安生物医药科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-113347883-B | Pesticidal compositions and methods | 科迪华农业科技有限责任公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116940562-A | Acetamido-phenylbenzamide derivatives and methods of use thereof | 希华医药有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-20230256106-A1 | DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF | COVAL BIOPHARMA (SHANGHAI) CO., LTD. (CN) | 2023-08-17 | — | — | US | disclosed |
| EP-4181963-A1 | DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF | Coval Biopharma (Shanghai) Co., Ltd. (CN) | 2023-05-24 | — | — | EP | disclosed |
| CN-115867319-A | Drug delivery system for local delivery of therapeutic agents and uses thereof | 上海椿安生物医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115232030-A | Aryl urea compound and preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2022-10-25 | — | — | CN | disclosed |
| CN-115044383-A | Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element | JSR株式会社 | 2022-09-13 | — | — | CN | disclosed |
| US-9249308-B2 | Compound having bisazo dye skeleton, pigment composition containing the same, pigment dispersion, ink, and color filter resist composition | CANON KABUSHIKI KAISHA (JP) | 2016-02-02 | — | — | US | disclosed |
| US-20150266882-A1 | PYRAZOLO[4,3-D]PYRIMIDINES AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20150259340-A1 | NOVEL KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| US-20140326931-A1 | NOVEL COMPOUND HAVING BISAZO DYE SKELETON, PIGMENT COMPOSITION CONTAINING THE SAME, PIGMENT DISPERSION, INK, AND COLOR FILTER RESIST COMPOSITION | CANON KABUSHIKI KAISHA (JP) | 2014-11-06 | — | — | US | disclosed |
| WO-2014060113-A1 | NOVEL KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2014-04-24 | — | — | WO | disclosed |
| WO-2014060112-A1 | PYRAZOLO[4,3-D]PYRIMIDINES AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2014-04-24 | — | — | WO | disclosed |
| WO-2010020556-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2010-02-25 | — | — | WO | disclosed |
| US-6727269-B1 | ACROMEGALY, PITUITARY ADENOMA OR ENDOCRINE GASTROENTEROPANCEATIC TUMORS INCLUDING THE CARCINOID SYNDROME, AND GASTROINTESTINAL BLEEDING | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-04-27 | — | — | US | disclosed |
| EP-1140855-A1 | TETRAHYDROINDAZOLE DERIVATIVES AS LIGANDS FOR GABA-A ALPHA 5 RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040565-A1 | TETRAHYDROINDAZOLE DERIVATIVES AS LIGANDS FOR GABA-A ALPHA 5 RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2000-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230256106-A1 | DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF | TIE1, TEK, KDR | NPC1 90/4885RAB9A 1413/4885LMNA 2725/4885 |
| US-20150259340-A1 | NOVEL KINASE INHIBITORS | LRRK2, MYLK2, MYLK | NPC1 4398/4885RAB9A 872/4885LMNA 3015/4885 |
| US-20150266882-A1 | PYRAZOLO[4,3-D]PYRIMIDINES AS KINASE INHIBITORS | LRRK2, MYLK2, MYLK | NPC1 4727/4885RAB9A 944/4885LMNA 3243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.