Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11593462 | 0.84 | TYR (0.41) | CYP3A4IDO1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3235233 | 0.82 | NPC1 (0.57) | LMNACYP3A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1936079 | 0.82 | LMNA (0.55) | LMNACYP3A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11593465 | 0.82 | HCAR2 (0.43) | CYP3A4NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8758151 | 0.82 | MET (0.56) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16244411 | 0.81 | LMNA (0.53) | LMNACYP3A4IDO1NPC1RAB9A | |
| SCHEMBL16244405 | 0.81 | LMNA (0.53) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5703716 | 0.81 | LMNA (0.53) | LMNACYP3A4IDO1NPC1RAB9A | |
| SCHEMBL15650450 | 0.81 | LMNA (0.53) | LMNAIDO1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL13777822 | 0.81 | ALDH1A1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |