SCHEMBL323567

SCHEMBL323567

O=C(O)c1ccc(-c2cccc(O)c2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.72
HSD17B1 P14061 4/20 0.68
HSD17B2 P37059 4/20 0.68
CYP3A4 P08684 2/20 0.68
CYP2C9 P11712 2/20 0.68
CHEK1 O14757 1/20 0.64
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA6 P23280 2/20 0.61
CA9 Q16790 2/20 0.61
TRIM24 O15164 1/20 0.61
TRIM33 Q9UPN9 1/20 0.61
RXRA P19793 4/20 0.59
RXRB P28702 4/20 0.59
RXRG P48443 1/20 0.59
BCL2 P10415 1/20 0.59
KMO O15229 1/20 0.57
KDM4E B2RXH2 1/20 0.55
LMNA P02545 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29876804 1.00 EGFR (0.72) EGFRHSD17B1HSD17B2CYP3A4CYP2C9
Benzoic Acid SCHEMBL23212129 0.90 CA12 (0.69) EGFRHSD17B1HSD17B2CYP3A4CYP2C9
SCHEMBL30066684 0.87 KMO (0.72) EGFRTRIM24TRIM33RXRARXRB
SCHEMBL16166011 0.87 KMO (0.72) EGFRTRIM24TRIM33RXRARXRB
SCHEMBL4677929 0.86 HSD17B1 (0.71) EGFRHSD17B1HSD17B2CYP3A4CYP2C9
SCHEMBL29876694 0.86 CA12 (0.76) EGFRHSD17B1HSD17B2CYP3A4CYP2C9
SCHEMBL4249787 0.86 CA12 (0.76) EGFRHSD17B1HSD17B2CYP3A4CYP2C9
SCHEMBL2346605 0.85 KMO (0.76) EGFRTRIM24TRIM33RXRARXRB
SCHEMBL29906143 0.85 KMO (0.76) EGFRTRIM24TRIM33RXRARXRB
Terephthalic Acid SCHEMBL4640732 0.85 CA12 (0.74) EGFRCYP3A4CHEK1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2167077-A2 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR Bayer Schering Pharma Aktiengesellschaft (DE) 2010-03-31 EP claimed
US-20090023741-A1 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR BAYER SCHERING PHARMA AG (DE) 2009-01-22 US claimed
WO-2008152099-A2 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-12-18 WO claimed
WO-1998014501-A1 PROCESS FOR THE PREPARATION OF THERMOTROPIC AROMATIC POLYESTERS DIRECTLY FROM DIALKYL AROMATIC ESTERS HOECHST CELANESE CORPORATION (US) 1998-04-09 WO claimed
US-5731401-A ONE STEP; HIGH MOLECULAR WEIGHT HOECHST CELANESE CORP. (US) 1998-03-24 US claimed
US-12448569-B2 Liquid crystalline polymer composition and molded article produced therefrom LOTTE CHEMICAL CORPORATION (KR) 2025-10-21 US disclosed
US-20250122425-A1 Liquid Crystalline Polymer Composition and Molded Article Produced Therefrom LOTTE CHEMICAL CORPORATION (KR) 2025-04-17 US disclosed
CN-117980412-A Liquid crystal polymer composition and molded article prepared therefrom 乐天化学株式会社 2024-05-03 CN disclosed
WO-2024043581-A1 INSULATION FILM AND LAMINATE COMPRISING SAME 코오롱인더스트리 주식회사 2024-02-29 WO disclosed
US-20240067600-A1 SMALL MOLECULE INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE (mtPTP) UNIVERSITY OF KANSAS (US) 2024-02-29 US disclosed
WO-2023239103-A1 LIQUID CRYSTAL POLYMER COMPOSITION AND MOLDED ARTICLE PRODUCED THEREFROM 롯데케미칼 주식회사 2023-12-14 WO disclosed
CN-116178687-A Wholly aromatic liquid crystal polyester and preparation method and application thereof 金发科技股份有限公司 2023-05-30 CN disclosed
WO-1999010308-A1 BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME GALDERMA RESEARCH & DEVELOPMENT (FR) 1999-03-04 WO disclosed
US-5770683-A Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
WO-1998014501-A1 PROCESS FOR THE PREPARATION OF THERMOTROPIC AROMATIC POLYESTERS DIRECTLY FROM DIALKYL AROMATIC ESTERS HOECHST CELANESE CORPORATION (US) 1998-04-09 WO disclosed
US-5731401-A ONE STEP; HIGH MOLECULAR WEIGHT HOECHST CELANESE CORP. (US) 1998-03-24 US disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed
EP-0044205-B1 POLYESTER OF 6-HYDROXY-2-NAPHTHOIC ACID AND METAHYDROXY BENZOIC ACID CAPABLE OF READILY UNDERGOING MELT PROCESSING CELANESE CORPORATION (US) 1985-04-10 EP disclosed
US-4337190-A Polyester of 6-hydroxy-2-naphthoic acid and meta-hydroxy benzoic acid capable of readily undergoing melt processing CELANESE CORPORATION (US) 1982-06-29 US disclosed
EP-0044205-A1 Polyester of 6-hydroxy-2-naphthoic acid and metahydroxy benzoic acid capable of readily undergoing melt processing CELANESE CORPORATION (US) 1982-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067600-A1 SMALL MOLECULE INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE (mtPTP) MTCH2, TIMM50, TIMM10 EGFR 4412/4885HSD17B1 2304/4885HSD17B2 2360/4885
US-20090023741-A1 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR PTGER2, PTGER1, PTGDR2 EGFR 888/4885HSD17B1 354/4885HSD17B2 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.