Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.76 |
| ▸ | CA1 | P00915 | 1/20 | 0.76 |
| ▸ | CA2 | P00918 | 1/20 | 0.76 |
| ▸ | CA6 | P23280 | 1/20 | 0.76 |
| ▸ | CA9 | Q16790 | 1/20 | 0.76 |
| ▸ | KMO | O15229 | 2/20 | 0.70 |
| ▸ | RXRA | P19793 | 2/20 | 0.61 |
| ▸ | RXRB | P28702 | 2/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876694 | 1.00 | CA12 (0.76) | CA12CA1CA2CA6CA9 | |
| Benzoic Acid SCHEMBL23212129 | 0.92 | CA12 (0.69) | CA12CA1CA2CA6CA9 | |
| SCHEMBL18788839 | 0.90 | KMO (0.68) | CA12CA1CA2CA6CA9 | |
| SCHEMBL30725957 | 0.89 | KMO (0.86) | CA12CA1CA2CA6CA9 | |
| SCHEMBL29904709 | 0.89 | KMO (0.86) | CA12CA1CA2CA6CA9 | |
| SCHEMBL71238 | 0.89 | KMO (0.86) | CA12CA1CA2CA6CA9 | |
| 3-Hydroxybenzoic Acid SCHEMBL8679140 | 0.87 | CA12 (1.00) | CA12CA1CA2CA6CA9 | |
| 3-Hydroxybenzoic Acid SCHEMBL9153881 | 0.87 | CA12 (1.00) | CA12CA1CA2CA6CA9 | |
| Fluoride SCHEMBL21332075 | 0.87 | KMO (0.83) | CA12CA1CA2CA6CA9 | |
| Hydrochloric Acid SCHEMBL21173951 | 0.87 | KMO (0.83) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178687-A | Wholly aromatic liquid crystal polyester and preparation method and application thereof | 金发科技股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| WO-2023017839-A1 | POLYESTER FILM AND METAL-CLAD LAMINATED BOARD | ＥＮＥＯＳ株式会社 | 2023-02-16 | — | — | WO | disclosed |
| CN-114891322-A | Wholly aromatic liquid crystal polyester composite material and preparation method and application thereof | 珠海万通特种工程塑料有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-107835680-B | Novel selective 11-beta-hydroxysteroid dehydrogenase type 1 | 帝斯曼知识产权资产管理有限公司 | 2021-11-09 | — | — | CN | disclosed |
| US-20210139521-A1 | DIARYL TREHALOSE COMPOUNDS AND USES THEREOF | THE UNIV OF MONTANA (US) | 2021-05-13 | — | — | US | disclosed |
| US-10550097-B2 | Selective 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors | DSM IP ASSETS B.V. (NL) | 2020-02-04 | — | — | US | disclosed |
| EP-3324924-B1 | NOVEL SELECTIVE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | DSM IP ASSETS BV (NL) | 2019-08-21 | — | — | EP | disclosed |
| US-20180208576-A1 | NOVEL SELECTIVE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | DSM IP ASSETS B.V. (NL) | 2018-07-26 | — | — | US | disclosed |
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2018-07-10 | — | — | US | disclosed |
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2018-07-10 | — | — | US | disclosed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |
| EP-0710684-B1 | Preparation process of polyhydroxycarboxylic acid | MITSUI CHEMICALS INC (JP) | 2001-01-31 | — | — | EP | disclosed |
| EP-0736018-B1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-6025375-A | INHIBITORY ACTIVITY ON PLATELET AGGREGATION, VASODILATING ACTIVITY, ANTIHYPERTENSIVE ACTIVITY OR THE LIKE AND ARE PROSTAGLANDIN I.SUB.2 AGONISTS, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| US-5770683-A | Preparation process of polyhydroxycarboxylic acid | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0736018-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0710684-A2 | Preparation process of polyhydroxycarboxylic acid | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995017393-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550097-B2 | Selective 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors | HSD11B1, HSD17B1, HSD3B1 | CA12 3860/4885CA1 2552/4885CA2 3821/4885 |
| US-20180208576-A1 | NOVEL SELECTIVE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | HSD11B1, HSD17B1, HSD3B1 | CA12 3604/4885CA1 2281/4885CA2 3757/4885 |
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | CTSE, CTSB, CTSS | CA12 2393/4885CA1 1457/4885CA2 1290/4885 |
| US-20210139521-A1 | DIARYL TREHALOSE COMPOUNDS AND USES THEREOF | TREH, STT3B, DDOST | CA12 757/4885CA1 1399/4885CA2 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.