Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234078 | 0.87 | HPGD (0.43) | LMNAHPGDGAAKDM4EKMT2A | |
| SCHEMBL3241080 | 0.80 | MPO (0.40) | GAAHDAC1 | |
| SCHEMBL3240737 | 0.78 | MAPK14 (0.48) | LMNAGAAKMT2AALDH1A1HDAC1 | |
| SCHEMBL3241850 | 0.78 | HDAC1 (0.34) | KDM4EHDAC1NPC1RAB9A | |
| SCHEMBL3233610 | 0.78 | KDM4E (0.38) | LMNAGAAKDM4EALDH1A1HDAC1 | |
| SCHEMBL3230365 | 0.77 | HDAC1 (0.43) | LMNAHPGDKMT2AALDH1A1HDAC1 | |
| SCHEMBL3238619 | 0.77 | KDM4E (0.34) | LMNAKDM4EALDH1A1HDAC1 | |
| SCHEMBL3235671 | 0.77 | GRM1 (0.44) | KMT2AHDAC1POLBMEN1NPC1 | |
| SCHEMBL3230345 | 0.76 | MLYCD (0.35) | HDAC1 | |
| SCHEMBL3227664 | 0.76 | HDAC1 (0.32) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028193-A1 | COMPOUNDS INCLUDING PIMELIC ACID DERIVATIVES AS HDAC INHIBITORS | REPLIGEN CORPORATION (US) | 2010-03-11 | — | — | WO | disclosed |