Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30332369 | 1.00 | CYP2A6 (0.56) | CYP2A6CNR2CYP11B2ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL4596482 | 0.98 | CYP2A6 (0.54) | CYP2A6CNR2CYP11B2ADORA2AADORA1 | |
| SCHEMBL1146096 | 0.83 | HDAC1 (0.51) | CNR2ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL29768457 | 0.83 | HDAC1 (0.51) | CNR2ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL3288734 | 0.81 | CNR2 (0.49) | CNR2CYP11B2ADORA2AADORA1ALDH1A1 | |
| SCHEMBL5826057 | 0.81 | HDAC1 (0.50) | CNR2ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL31267979 | 0.80 | CNR2 (0.49) | CNR2CYP11B2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL10000582 | 0.79 | CYP2A6 (0.49) | CYP2A6CNR2CYP11B2CYP1A2CNR1 | |
| SCHEMBL17116598 | 0.79 | CNR2 (0.47) | CNR2CYP11B2ALDH1A1CYP11B1KDM4E | |
| SCHEMBL3292911 | 0.78 | CNR2 (0.57) | CYP2A6CNR2CYP11B2CYP11B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273070-B2 | Organozinc complexes and processes for making and using the same | KNOCHEL PAUL (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9273070-B2 | Organozinc complexes and processes for making and using the same | KNOCHEL PAUL (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20140031545-A1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | LUDWIG-MAXIMILIAN-UNIVERSITAT MUNCHEN (DE) | 2014-01-30 | — | — | US | disclosed |
| US-20140031545-A1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | LUDWIG-MAXIMILIAN-UNIVERSITAT MUNCHEN (DE) | 2014-01-30 | — | — | US | disclosed |
| US-8546374-B2 | Amino-tetrazoles analogues and methods of use | ABBVIE INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120329772-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2012-12-27 | — | — | US | disclosed |
| US-8217067-B2 | Antiinflammatory agents, antidepressants, analgesics, purinergic receptor antagonists; neurodegenerative diseases, spinal cord injuries; 1-(2,3-dichlorophenyl)-N-[(2-methylphenyl)methyl]-1H-tetraazol-5-amine | ABBOTT LABORATORIES (US) | 2012-07-10 | — | — | US | disclosed |
| EP-2201011-A2 | NOVEL COMPOUNDS HAVING INDAZOLE FRAMEWORKS, METHODS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Choongwae Pharma Corporation (KR) | 2010-06-30 | — | — | EP | disclosed |
| US-7723367-B2 | Amino-tetrazoles analogues and methods of use | ABBOTT LABORATORIES (US) | 2010-05-25 | — | — | US | disclosed |
| US-7704997-B1 | Amino-tetrazole analogues and methods of use | ABBOTT LABORATORIES (US) | 2010-04-27 | — | — | US | disclosed |
| WO-2010027114-A1 | USE OF PYRAZOLE-PYRIDINE DERIVATIVES AND ITS SALTS FOR TREATING OR REVENTIN OSTEOPOROSIS | CHOONGWAE PHARMA CORPORATION (KR) | 2010-03-11 | — | — | WO | disclosed |
| WO-2009038385-A2 | NOVEL COMPOUNDS HAVING INDAZOLE FRAMEWORKS, METHODS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHOONGWAE PHARMA CORPORATION (KR) | 2009-03-26 | — | — | WO | disclosed |
| US-20080171733-A1 | Amino-Tetrazoles Analogues and Methods of Use | ABBOTT LABORATORIES (US) | 2008-07-17 | — | — | US | disclosed |
| US-20070049584-A1 | Amino-tetrazoles analogues and methods of use | ABBVIE INC. | 2007-03-01 | — | — | US | disclosed |
| EP-1747206-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2007-01-31 | — | — | EP | disclosed |
| US-20060052374-A1 | Amino-tetrazole analogues and methods of use | ABBVIE INC. | 2006-03-09 | — | — | US | disclosed |
| WO-2005111003-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031545-A1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | ODC1, AOC1, ADH1C | CYP2A6 1992/4885CNR2 3616/4885CYP11B2 887/4885 |
| US-20080171733-A1 | Amino-Tetrazoles Analogues and Methods of Use | P2RX7, P2RX2, P2RX5 | CYP2A6 1918/4885CNR2 97/4885CYP11B2 678/4885 |
| US-20120329772-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | P2RX7, P2RX2, P2RX5 | CYP2A6 1918/4885CNR2 97/4885CYP11B2 678/4885 |
| US-20070049584-A1 | Amino-tetrazoles analogues and methods of use | P2RX7, P2RX2, P2RX5 | CYP2A6 1918/4885CNR2 97/4885CYP11B2 678/4885 |
| US-20060052374-A1 | Amino-tetrazole analogues and methods of use | P2RX7, P2RX2, P2RX3 | CYP2A6 1828/4885CNR2 112/4885CYP11B2 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.