SCHEMBL2771199

SCHEMBL2771199

O=C(O)c1ccc(-c2ccc(C(=O)O)cc2O)c(O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.73
CA1 P00915 4/20 0.73
CA2 P00918 4/20 0.73
CA6 P23280 4/20 0.73
CA9 Q16790 4/20 0.73
CA4 P22748 3/20 0.73
CA7 P43166 3/20 0.73
CA14 Q9ULX7 3/20 0.73
KDM4E B2RXH2 2/20 0.73
MAPT P10636 2/20 0.73
POLB P06746 2/20 0.73
GAA P10253 1/20 0.73
PTGS2 P35354 1/20 0.73
L3MBTL1 Q9Y468 1/20 0.73
TP53 P04637 2/20 0.56
CA3 P07451 2/20 0.56
CA5A P35218 2/20 0.56
CA5B Q9Y2D0 2/20 0.56
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12023160 0.91 CA12 (0.61) CA12CA1CA2CA6CA9
SCHEMBL6537037 0.89 TTR (0.60) CA12CA1CA2CA6CA9
SCHEMBL26981142 0.88 KDM4E (0.64) CA12CA1CA2CA6CA9
SCHEMBL3238016 0.86 CA12 (0.61) CA12CA1CA2CA6CA9
SCHEMBL3663963 0.84 POLB (0.59) CA12CA1CA2CA6CA9
Protocatechuic Acid SCHEMBL30030432 0.84 CA12 (1.00) CA12CA1CA2CA6CA9
Protocatechuic Acid SCHEMBL39435 0.84 CA12 (1.00) CA12CA1CA2CA6CA9
Protocatechuic Acid SCHEMBL29350008 0.84 CA12 (1.00) CA12CA1CA2CA6CA9
Protocatechuic Acid SCHEMBL27815804 0.84 CA12 (1.00) CA12CA1CA2CA6CA9
SCHEMBL28211489 0.83 HSD17B10 (0.58) CA12CA1CA2CA6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630567-B2 High yield synthesis of metal-organic frameworks ExxonMobil Technology and Engineering Company (US) 2026-05-19 US claimed
CN-119833885-A Polymer-ceramic integrated lithium battery diaphragm coating and preparation method and application thereof 河北金力新能源科技股份有限公司 2025-04-15 CN claimed
CN-119059895-A Preparation method of 2,2 '-dihydroxybiphenyl-4, 4' -dicarboxylic acid 黑龙江省科学院石油化学研究院 2024-12-03 CN claimed
US-20240199478-A1 High Optical Transmission Amphiphobic Surfaces; and Methods of Forming Them UCL BUSINESS LTD (GB) 2024-06-20 US claimed
EP-3856748-B1 METAL-ORGANIC FRAMEWORK PHASE AND CRYSTALLITE SHAPE CONTROL UNIV CALIFORNIA (US) 2024-03-06 EP claimed
US-11872537-B2 Metal-organic frameworks for carbon dioxide capture ExxonMobil Technology and Engineering Company (US) 2024-01-16 US claimed
EP-4301711-A1 HIGH OPTICAL TRANSMISSION AMPHIPHOBIC SURFACES; AND METHODS OF FORMING THEM UCL Business Ltd (GB) 2024-01-10 EP claimed
US-20230173426-A1 AMINE-APPENDED METAL-ORGANIC FRAMEWORKS EXHIBITING A NEW ADSORPTION MECHANISM FOR CARBON DIOXIDE SEPARATIONS U.S. DEPARTMENT OF ENERGY 2023-06-08 US claimed
US-20230151028-A1 High Yield Synthesis Of Metal-Organic Frameworks ExxonMobil Technology and Engineering Company 2023-05-18 US claimed
US-11458431-B2 Amine-appended metal-organic frameworks exhibiting a new adsorption mechanism for carbon dioxide separations THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-10-04 US claimed
EP-3703842-A1 POLYAMINE-APPENDED METAL-ORGANIC FRAMEWORKS FOR CARBON DIOXIDE SEPARATIONS The Regents of The University of California (US) 2020-09-09 EP claimed
EP-3661645-A1 OVERCOMING TWO CARBON DIOXIDE ADSORPTION STEPS IN DIAMINE-APPENDED METAL-ORGANIC FRAMEWORKS The Regents of The University of California (US) 2020-06-10 EP claimed
EP-3661644-A1 METAL ORGANIC FRAMEWORKS APPENDED WITH CYCLIC DIAMINES FOR CARBON DIOXIDE CAPTURE The Regents of The University of California (US) 2020-06-10 EP claimed
WO-2020068996-A1 METAL-ORGANIC FRAMEWORK PHASE AND CRYSTALLITE SHAPE CONTROL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-04-02 WO claimed
US-20200101439-A1 METAL-ORGANIC FRAMEWORK PHASE AND CRYSTALLITE SHAPE CONTROL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-04-02 US claimed
US-20190126237-A1 POLYAMINE-APPENDED METAL-ORGANIC FRAMEWORKS FOR CARBON DIOXIDE SEPARATIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2019-05-02 US claimed
US-20190039015-A1 METAL-ORGANIC FRAMEWORKS APPENDED WITH CYCLIC DIAMINES FOR CARBON DIOXIDE CAPTURE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-02-07 US claimed
WO-2018152438-A1 AMINE-APPENDED METAL-ORGANIC FRAMEWORKS EXHIBITING A NEW ADSORPTION MECHANISM FOR CARBON DIOXIDE SEPARATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-08-23 WO claimed
US-8188316-B2 Integrated process for the preparation of polybenzimidazole precursors E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-29 US claimed
US-20100160679-A1 INTEGRATED PROCESS FOR THE PREPARATION OF POLYBENZIMIDAZOLE PRECURSORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160679-A1 INTEGRATED PROCESS FOR THE PREPARATION OF POLYBENZIMIDAZOLE PRECURSORS DDC, DDT, PDCD2L CA12 2175/4885CA1 2537/4885CA2 1415/4885
US-20190039015-A1 METAL-ORGANIC FRAMEWORKS APPENDED WITH CYCLIC DIAMINES FOR CARBON DIOXIDE CAPTURE AMPD2, AMPD1, AMPD3 CA12 1022/4885CA1 492/4885CA2 33/4885
US-12630567-B2 High yield synthesis of metal-organic frameworks ODC1, POF1B, DDC CA12 46/4885CA1 20/4885CA2 9/4885
US-20200101439-A1 METAL-ORGANIC FRAMEWORK PHASE AND CRYSTALLITE SHAPE CONTROL POF1B, BMX, MB CA12 9/4885CA1 11/4885CA2 8/4885
US-11872537-B2 Metal-organic frameworks for carbon dioxide capture MT-CO2, TMCO1, SLC6A12 CA12 13/4885CA1 28/4885CA2 15/4885
US-20230151028-A1 High Yield Synthesis Of Metal-Organic Frameworks MAX, POF1B, CPSF1 CA12 80/4885CA1 188/4885CA2 64/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.