Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16034061 | 0.78 | EPHX1 (0.46) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL6787716 | 0.76 | KDM4E (0.39) | EPHX1CPA1CYP1A2ACECES1 | |
| SCHEMBL2059538 | 0.76 | EPHX1 (0.44) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL5609146 | 0.76 | ACE (0.53) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL6380241 | 0.76 | EPHX1 (0.56) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL838906 | 0.76 | MEN1 (0.46) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL10693279 | 0.76 | EPHX1 (0.44) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL7256073 | 0.76 | EPHX1 (0.44) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL5609280 | 0.76 | CPA1 (0.46) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL5609144 | 0.76 | EPHX1 (0.44) | EPHX1TAAR1SLC6A2SIGMAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372848-B2 | N-benzylamino cyclic thioureas; obesity and related disorders; (N-(3-{(4S)-1-[(1S)-2-(benzylamino)-1-methylethyl]-3-[2-(3-fluorophenyl)ethyl]-2-thioxoimidazolidin-4-yl}propyl)guanidine | MIXTURE SCIENCES, INC. (US) | 2013-02-12 | — | — | US | claimed |
| EP-1727540-A4 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AND METHODS OF USE | UNIV CALIFORNIA (US) | 2009-07-22 | — | — | EP | claimed |
| US-20080255218-A1 | Melanin-Concentrating Hormone Receptor Antagonists and Methods of Use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-16 | — | — | US | claimed |
| EP-1727540-A1 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AND METHODS OF USE | The Regents Of the University of California (US) | 2006-12-06 | — | — | EP | claimed |
| WO-2005094817-A1 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-10-13 | — | — | WO | claimed |
| JP-59027849-A | — | — | None | — | — | JP | disclosed |
| JP-59027838-A | — | — | None | — | — | JP | disclosed |
| US-8709704-B2 | Pattern forming method using developer containing organic solvent and rinsing solution for use in the pattern forming method | FUJIFILM CORPORATION (JP) | 2014-04-29 | — | — | US | disclosed |
| US-8372848-B2 | N-benzylamino cyclic thioureas; obesity and related disorders; (N-(3-{(4S)-1-[(1S)-2-(benzylamino)-1-methylethyl]-3-[2-(3-fluorophenyl)ethyl]-2-thioxoimidazolidin-4-yl}propyl)guanidine | MIXTURE SCIENCES, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| US-20120322007-A1 | PATTERN FORMING METHOD, CHEMICAL AMPLIFICATION RESIST COMPOSITION AND RESIST FILM | FUJIFILM CORPORATION (JP) | 2012-12-20 | — | — | US | disclosed |
| US-20110229832-A1 | PATTERN FORMING METHOD USING DEVELOPER CONTAINING ORGANIC SOLVENT AND RINSING SOLUTION FOR USE IN THE PATTERN FORMING METHOD | FUJIFILM CORPORATION (JP) | 2011-09-22 | — | — | US | disclosed |
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-1727540-A1 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AND METHODS OF USE | The Regents Of the University of California (US) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005094817-A1 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-10-13 | — | — | WO | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-4567293-A | ANTIINFLAMMATORY | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-01-28 | — | — | US | disclosed |
| JP-S5927849-A | 2-(4-(2-TRIFLUOROMETHYL-3,3,3-TRIFLUOROPROPYL)PHENYL) PROPIONIC ACID OR ITS SALT AND ANTIPHLOGISTIC AGENT CONTAINING SAID COMPOUND | KUREHA CHEM IND CO LTD | 1984-02-14 | — | — | JP | disclosed |
| JP-S5927838-A | 3,3,3-TRIFLUORO-2-TRIFLUOROMETHYLPROPYLBENZENE AND ITS PREPARATION | KUREHA CHEM IND CO LTD | 1984-02-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110229832-A1 | PATTERN FORMING METHOD USING DEVELOPER CONTAINING ORGANIC SOLVENT AND RINSING SOLUTION FOR USE IN THE PATTERN FORMING METHOD | RER1, RARA, RARG | EPHX1 416/4885TAAR1 2341/4885SLC6A2 3795/4885 |
| US-20080255218-A1 | Melanin-Concentrating Hormone Receptor Antagonists and Methods of Use | MCHR1, MCHR2, MC1R | EPHX1 3325/4885TAAR1 51/4885SLC6A2 203/4885 |
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | EPHX1 3756/4885TAAR1 436/4885SLC6A2 1969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.