Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.37 |
| ▸ | ITGAV | P06756 | 4/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233025 | 0.91 | SLC6A9 (0.39) | SLC6A9ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL3245881 | 0.90 | SLC6A9 (0.39) | SLC6A9LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3241373 | 0.89 | ALDH1A1 (0.39) | SLC6A9ITGB3LMNASMN1; SMN2MEN1 | |
| SCHEMBL3243734 | 0.88 | SLC6A9 (0.48) | SLC6A9LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3238301 | 0.87 | SLC6A9 (0.47) | SLC6A9LMNAMEN1KMT2ANPC1 | |
| SCHEMBL3234880 | 0.87 | CCR5 (0.41) | CCR5SLC6A9LMNASMN1; SMN2MEN1 | |
| SCHEMBL3244977 | 0.84 | TACR1 (0.39) | SLC6A9 | |
| SCHEMBL3239948 | 0.84 | KMT2A (0.38) | ITGB3LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3237806 | 0.83 | ROCK2 (0.43) | SLC6A9LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL26840793 | 0.82 | RXFP1 (0.38) | SLC6A9LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745642-B2 | Glycine transport inhibitors | GLAXO GROUP LIMITED (GB) | 2010-06-29 | — | — | US | disclosed |
| US-7745642-B2 | Glycine transport inhibitors | GLAXO GROUP LIMITED (GB) | 2010-06-29 | — | — | US | disclosed |
| US-7745642-B2 | Glycine transport inhibitors | GLAXO GROUP LIMITED (GB) | 2010-06-29 | — | — | US | disclosed |
| US-20080287547-A1 | Glycine Transport Inhibitors | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| US-20080287547-A1 | Glycine Transport Inhibitors | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287547-A1 | Glycine Transport Inhibitors | SLC18A2, SLC6A5, SLC1A2 | CCR5 4457/4885SLC6A9 13/4885ITGB3 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.