Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243682 | 0.88 | MAPT (0.36) | LMNAKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3243453 | 0.88 | MEN1 (0.40) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3246762 | 0.85 | CYP3A4 (0.41) | ALDH1A1HTTTSHRLMNAKDM4E | |
| SCHEMBL3246780 | 0.85 | CYP3A4 (0.41) | ALDH1A1HTTTSHRLMNAKDM4E | |
| SCHEMBL3249870 | 0.69 | MAPT (0.37) | ALDH1A1LMNAKMT2A | |
| SCHEMBL3242922 | 0.68 | HTR2C (0.34) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28377112 | 0.66 | SLC6A3 (0.43) | — | |
| SCHEMBL3243448 | 0.66 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL3243831 | 0.66 | KMT2A (0.44) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL8689935 | 0.66 | NOTUM (0.41) | ALDH1A1HTTTSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102204-B1 | NEW AMINOPYRROLO[1,2- A]INDOLE ET AMINOPYRIDAZINO[1,6-A]INDOLE DERIVATIVES, METHOD FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SERVIER LAB (FR) | 2010-05-05 | — | — | EP | disclosed |